Chapter 32 - Guyton

Question 1

Pluripotent stem cells develop into either?

Answer 1

lymphoid or myeloid stem cell

Question 2

Lymphoid stem cells develop into either?

Answer 2

T-cell and B-cell

Question 3

Myeloid stem cells develop into?

Answer 3

eosinophil, basophil, neutrophil, monocyte (macrophage), platelets, erythrocyte

Question 4

Main function of erythrocytes (RBCs).

Answer 4

transport hemoglobin

Question 5

Normal hematocrit.

Answer 5

40-45%

Question 6

Iron is transported in the blood in which form?

Answer 6

ferrous

Question 7

Hormone released from kidney in response to low renal oxygenation.

Answer 7

erythropoietin (stimulates stem cell formation of pronormoblasts, release of reticulocytes, increase in red cell number in 5 days)

Question 8

Where is erythropoietin produced?

Answer 8

peritubular interstitial cells of the kidney (always present in the plasma)

Question 9

Normal Hg levels.

Answer 9

15-16 (male) gm Hg/100 mL blood, 13-14 (female) gm Hg/100 mL blood

Question 10

Normal oxygen carrying capacity.

Answer 10

~21 ml O2/100 mL blood men, ~19 ml O2/100 mL blood women

Question 11

If hematocrit is low, the percentage of reticulocytes will be greater/lower.

Answer 11

greater

Question 12

Primary site of hemopoietic activity in adults.

Answer 12

bone marrow

Question 13

Hemoglobin excreted as?

Answer 13

bilirubin

Question 14

Plasma levels indicative of iron deficiency.

Answer 14

ferritin

Question 15

Sites of functional iron vs. storage iron.

Answer 15

functional - RBCs, muscle, bone marrow

storage - liver, monocytes/macrophages