Normal Na value?
135-145 mEq/L
What are the 3 different types of hyponatremia?
1) Hypertonic
- sosmol > 295, Na < 135
2) Isotonic
- norm sosmol, Na < 135
3) Hypotonic (true hyponatremia)
- sosmol < 275, Na < 135
What lab values support a diagnosis of Hypertonic Hyponatremia?
sosmol > 295 and Na < 135
What lab values support a diagnosis of Hypotonic Hyponatremia?
sosmol < 275 and Na < 135
What lab values support a diagnosis of Isotonic Hyponatremia?
sosmol 275 - 295 and Na < 135
What is the normal serum osmolality value?
275-295 mOsm/kg
What is the normal serum sodium range?
135-145 mEq/L
Which type of hyponatremia is called the “true hyponatremia”?
Hypotonic Hyponatremia
What are the main causes of hyponatremia?
Antidiuretic Hormone (ADH) is released from what organ?
Anterior Pituitary gland
What are the symptoms of hyponatremia?
SALTLOSS
- Stupor or coma
- Anorexia
- Lethargy
- decreased Tendon reflexes
- Limp muscles / weakness
- Orthostatic hypotension
- Seizures
- Stomach cramping
What is the acronym used to remember the symptoms of hyponatremia?
SALTLOSS
What are the diagnostic tests used to diagnose hyponatremia?
What is the cause of hypertonic hyponatremia?
there is an increase in another solute which causes increased Na loss from kidneys
- ex: hyperglycemia
What is the first step when assessing a patient with hypotonic hyponatremia?
What is the treatment for a patient with hypotonic hyponatremia and is fluid overloaded?
what is normal urine Na levels?
10-20 mEq/L
In a patient that with hypotonic (mOsm < 275) hyponatremia (Na < 135) and is volume depleted, how can you tell if a patient is loosing fluids through the GI tract or diaphoresis vs renally?
check Urine Na levels (normal is 10-20 mEq/L)
- < 10 = GI / diaphoresis
- > 20 = renal (most common cause is overuse of diuretics)
What is the treatment a hyponatremic patient is overcorrected?
start D5W and ddAVP (desmopresin) which is a synthetic anti diuretic hormone
How much does 10 mEq of KCL raise the serum postassium?
approximately 0.1 mEq/L