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Flashcards in Erythrocytes (RBC's) Deck (18)
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1

describe the shape of the erythrocytes

biconcave

2

why is the erythrocytes biconcave?

because it lost it's nucleus and has no organelles

3

what are the functions of the erythrocytes?

1. carry oxygen to tissues
2. removal of carbon dioxide

4

are erythrocytes flexible?

very flexible

5

what is the life span the erythrocytes?

110-120 days

6

what is the problem of erythrocytes?

1. it does not have it's nucleus
2. it does not have DNA
3. it can not repair itself
4. it can not reproduce

7

what is the flexibility of the erythrocyte?

the flexibility of the cell allows it to adapt readily to irregular shapes and sizes of capillaries

8

explain one amino acid substitution

one amino acid substitution in the beta chain of hemoglobin renders it insoluble (brittle; inflexible)

9

what are the results of the substitution?

if you get one amino acid wrong you get sickle cell anemia

10

what is the hemoglobin of the erythrocytes?

4 heme groups and one Fe++

11

when hemoglobin binds w/oxygen you get

oxyhemoglobin

12

when hemoglobin binds w/carbon dioxide you get

carbamino hemoglobin

13

are oxyhemoglobin and carbamino hemoglobin reversible of irreversible?

reversible

14

when hemoglobin binds w/carbon monoxide you get

carboxyhemoglobin which is NOT reversible

15

how do we get different blood cells?

1. cell membrane
2. glycophorin binding

16

explain cell membrane

cell membrane contains integral membrane proteins

17

explain glycophorin binding

glycophine binding different oligosaccharide chains

18

the composition of these chains will determine what?

will determine your blood type