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Flashcards in Exam questions-Milner Deck (4)
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1
Q

T/F: macrophages play no role in the body’s immune response to cancer

A

False

2
Q

T/F: With MHC restricted tumor antigen presentation, lack of inflammation and lack of costimulatory molecule expression can lead to tolerance

A

True

3
Q

Killing of cancer cells in the body by NK-cells is thought to be primarily mediated by

A

CD95/CD95 ligand receptor interactions

4
Q

What are some reasons for failure of the immune response in cancer patients

A

Development of tolerance
Down regulation of MHC-1 receptors on cancers
Suppressor cells
Blocking antibodies