FDA

Question 1

FDA whole body SAR

Answer 1

4 w/kg at 15 mins

Question 2

FDA head SAR

Answer 2

3 w/kg at 10 minutes

Question 3

FDA head or torso SAR

Answer 3

8 w/kg at 5 minutes

Question 4

FDA extremities SAR

Answer 4

12 w/kg at 5 minutes

Question 5

ADC Values:
Normal Tissue:

• CSF
• Grey Matter
• White Matter

not for registry*

Answer 5

• CSF - 3000 - 4000 mm2/s (bright)
• Grey Matter - 700 - 100 mm2/s
• White Matter - 670 - 800 mm2/s (dark)

Question 6

ADC Values:
Pathological tissue:
* Grade II, Glioblastoma
* Grade III, Glioblastoma
* Grade IV, Glioblastoma
* Acute Infarct

not for registry*

Answer 6

Grade II, Glioblastoma - 1200 mm2/s (dark)
Grade III, Glioblastoma - 1000 mm2/s
Grade IV, Glioblastoma - 800 mm2/s
Acute Infarct - 400 mm2/s (bright)