What is the child at risk for?
a. Normal finding
b. Neurofibromatosis
c. Melanoma
d. Tinea versicolor
b. Neurofibromatosis
Rationale: Described above is Café au Lait Macule. If a patient has 6 or more or larger than 1.5 cm the patient is at high risk for Neurofibromatosis.
Which of the following considerations is not true for prescribing Isotretinoin?
a. Isotretinoin can be prescribed by any healthcare provider.
b. Isotretinoin is a category X drug and requires 2 forms of contraception, one of which can be abstinence.
c. Before use of Isotretinoin, the patient must sign an informed consent and become enrolled in a monitoring program called iPledge.
d. If a patient’s acne relapses on Isotretinoin, then they may complete a second round of the therapy.
a. Isotretinoin can be prescribed by any healthcare provider.
Rationale: The correct answer is A. Isotretinoin (Accutane) can only be prescribed by providers who are registered with the iPledge program. Providers must be aware of all the potential serious side effects and monitoring that is required for this treatment.
c. Hemangioma
Rationale: Hemangiomas are often present at birth as a blanched area on the skin, then within a few weeks to a month starts to turn into a vascular, red, rubbery nodule.
Mongolian spots are usually found on the low back near the pelvis and are a dark blue/black. Port-wine stains are a darker red and are flat.
Melanocytic nevi are a very dark brown and are flatter than hemangiomas.

d. Scabies

Rationale: Scabies classically presents with linear burrows at the wrists, ankles, webbing of fingers, areola, axillary folds, and genital area and typically does not involve the face except in infants. Excoriations are also a common finding with this. The history of recently travel and other family members with similar presentation also supports scabies as the leading choice.
All other choices are commonly occurring rashes in pediatrics but have different presentations.
b. Clobetasol (Temovate) 0.05% ointment
Rationale: Potent topical corticosteroids like clobetasol are first line treatment for psoriasis. This is needed to penetrate through the plaques which occur because of epidermal cell proliferation beyond normal turnover.
Ketoconazole is not a topical steroid.
Hydrocortisone 1% is a topical steroid but is low potency.
Systemic steroids like prednisone can cause severe rebound in psoriasis and are not appropriate

a. Impetigo

Rationale: Macules, vesicles, pustules, that are often honey-colored and crust over are the tell-tale sign of impetigo.
This highly contagious infection is caused by staphylococcus and streptococci and is common in infants and children as it is spread by skin-to-skin contact.
a. Rosacea
Rationale: Blepharitis is an inflammatory condition that effects the eyelids, usually caused by an overgrowth of bacteria, specifically staphylococci.
Meibomian glandular dysfunction is another cause of blepharitis, which is strongly correlated with rosacea.
Symptoms of blepharitis include redness, tearing, photophobia, and a foreign body sensation that feels dry and gritty.
Treatment usually consists of good eyelid hygiene and washing the eyelids with baby shampoo.

a. Port wine nevus on the face
Rationale: Port wine nevus on the face is correct and usually a feature of SWS.
Mongolian spot is incorrect and is a benign darkening of the skin (most often on the buttocks) found in Asian and African descent infants. This is not associated with SWS.
Allergic shiners are dark areas under the eyes usually seen with allergic rhinitis.
Retractions is incorrect as this indicates an acute respiratory issue.

a. Tinea Versicolor
Rationale: KOH test will show large thick-walled spores with blunt hyphae. Yeast is best seen under microscopic examination; cultures are not suggested for they are not useful in diagnosing this yeast disorder.
Tinea versicolor is typically a recurrent problem due to yeast that is a colonizer to all humans making the rate of relapse likely after treatment is completed.

a.Watchful approach is appropriate as these lesions typically fade as the child ages
Rationale: A hemangioma is a red, rubbery nodule that is becomes noticeable around 2-4 weeks of age and rapidly grows in size within the first 5-7 weeks of life. Growth stabilizes around 9-12 months of age and reaches maximal regression between ages 5-9 years.
Hemangiomas are typically benign tumors of capillary endothelial cells that are superficial, deep or a mixture of both. They can be anywhere on the body and size greatly varies. The term “strawberry” is widely used but can be misleading and should not be used to describe the nodules.
c. Inguinal
Rationale: Hiatal and paraoesophageal hernias are disorders of the proximal end of the GI tract and are associated with dysphagia, vomiting, heartburn, regurgitation, failure to thrive, and pulmonary infections.
Umbilical hernias occur more frequent in full term African American infants and most spontaneous regress by age 4, location is as suggested by umbilicus.
Inguinal hernias are most common if male (9:1), preterm, and have a ‘silk glove’ feel when the area is rubbed together and located well below the umbilicus.

b. History of peptic ulcer disease and prescribe a PPI along with an NSAID
Rationale: H Pylori infection and NSAID use are the two major causes of peptic ulcer disease.
Risk factors that increase incident of peptic ulcer disease in patients taking NSAIDs includes previous PUD or GI bleed, age over 65 years.
Concomitant use of a daily proton pump inhibitor, such as omeprazole, with NSAIDs is recommended to decrease the risk of PUD.
Meloxicam: Nonsteroidal anti-inflammatory drug. It can treat osteoarthritis (OA) and rheumatoid arthritis (RA).
c. Increased gastrointestinal motility
Rationale- Delayed gastrointestinal motility is a consequence of DMD that can induce debilitating constipation, which can limit patients’ mobility, cause pain, and lower their quality of life.
What are the key characteristics of Duchenne muscular dystrophy?
Duchenne Muscular Dystrophy

a. Rheumatoid Arthritis
Rational: Rheumatoid arthritis usually has a slow onset and worsens over time. The pain is most often worse in the mornings. It most often affects the joints of the fingers.
Signs and symptoms of RA include:
c. Osteopenia

Rationale: It is recommended to screening all women over the age of 65 for bone mineral density.
The T score represents the number of standard deviations from the norm.
A normal score is +1 to -1.
Scores between -1.0 and -2.5 indicate osteopenia.
Scores between -2.5 or lower indicate osteoporosis.
c. Initial treatment of SCFE is non-weight bearing status with the use of crutches and a referral to an orthopedic surgeon.
Rationale: Slipped capital femoral epiphysis (SCFE) refers to the displacement of the proximal femoral epiphysis due to the disturbance of the growth plate.
This condition is usually seen in teenage, overweight males.
It occurs when the proximal femoral physis is strained or resistance to shear is reduced.
Physical inspection regularly reveals a weakness of internal rotation of the hip.
Initial management consists of making the patients use crutches and observe non-weight bearing status. Immediate referral to an orthopedic surgeon is also warranted.
Typically, SCFE occurs in overweight children between 11 and 16 years old and is more common in boys than girls. SCFE occurs more frequently in African Americans and Hispanic children than Caucasians. It is also more likely to occur in children going through rapid growth spurts.
Symptoms of SCFE include pain in your teen’s groin, knee or hip; walking with a limp and inability to bear weight on the leg. Surgery is needed.

c. Serial spinal x-rays, bracing, and frequent observation rather than surgery
Rationale: Scoliosis refers to a lateral curvature of the spine that typically affects adolescent girls.
Treatment of scoliosis depends on the degree of curvature of the spine that can be measured by the Cobb angle or a standing PA x-ray.
Curvatures less than 20 degrees typically do not need management unless they show progression.
Bracing is indicated for curvatures of 20-40 degrees in a skeletally immature child.
Bracing will not help curvatures greater than 40 degrees, and curvatures greater than 70 degrees will most likely progress.
Thus, surgical correction is indicated for curvatures between 40-60 degrees.
b. MRI
Rationale: Although ultrasounds are sometimes helpful, an MRI is the best way to visualize a rotator cuff.
An x-ray would not yield sufficient imaging for this type of injury. X-rays are more helpful in visualizing bones.
d. Running on a treadmill
Rationale: Treating symptoms along with lifestyle modifications are helpful in improving quality of life in osteoarthritis.
Avoiding high impact activity and wearing proper shoes are key components in lessening pain
a. Hypermobility syndrome
Rationale: Laxity causes improper joint alignment during exercise which causes joint pain
Symptoms of joint hypermobility syndrome