CD surface marker found on all NK cells and binds constant region of IgG
CD16
CD surface marker that inhibits complement C9 binding
CD55
CD59
CD surface marker that is an endotoxin receptor found on macrophages
CD14
Primary immune system cell type involved in host tumor immune surveillance
Cytotoxic T cells
How might tumor cells induce apoptosis of T cells that would antagonize them?
Expressing FasL (death receptor) This is seen in melanoma, hepatocellular CA, etc.
Enzyme present in melanoma that generates peptides that are targets for host T cells
Tyrosinase
Cytokines produced by Th1 cells
IL-2, IFN-y
Activation of CD8 and macrophages
Cytokines produced by Th2 cells
IL-4, Il-5, IL-10
Activation of B cells, Ab production
What are the 3 acute phase cytokines?
IL-1
IL-6
TNF alpha