1
Q
how big are small synaptic vesicles (SSV)?
A
50 nm diameter
2
Q
how big are large dense core vesicles (LDCV)?
A
100 nm diameter
3
Q
what classical neurotransmitters do SSV’s contain?
A
glutamate, GABA, glycine
4
Q
what do LDCV’s contain?
A
catecholamines (adrenaline, noradrenaline), neuropeptides (neuropeptide Y), neurotrophins (BDNF)
5
Q
SSV’s are electron lucent, meaning…?
A
they don’t have large proteins
6
Q
LDCV’s are electron-dense (dark), meaning…?
A
they are packed full of large molecules/proteins
7
Q
what do SSV’s and LDCV’s have in common?
A
both are membrane bound
8
Q
where is majority of transmission in CNS derived from?
A
SSV’s
9
Q
where is majority of transmission in PNS derived from?
A
LDCV’s
