What is aphasia?
Disorder of speech
Where is language processed in the brain?
Dominant hemisphere (usually left)
Broca’s area
Wernicke’s area
What is Broca’s aphasia?
Where is Broca’s area?
Brodmann’s area 44/45
What kind of damage causes Broca’s aphasia?
What is Wernicke’s aphasia?
Where is Wernicke’s area?
Brodmann’s area 22
What kind of damage causes Wernicke’s aphasia?
What connects Broca’s and Wernicke’s areas?
Arcuate fasciculus
What is the arcuate fasciculus
Connects Broca’s and Wernicke’s areas
Fibre tracts
What is conduction aphasia?
Damage to fibre tracts connecting Broca’s and Wernicke’s areas
Impairment in repetition of spoken word
Absence of spontaneous speech deficits or word comprehension
Which experiments have confirmed the laterality of language processing?
2. The WADA procedure
What occurred in the split brain experiments?
What kind of stimuli does the right hemisphere primarily respond to?
Non-verbal stimuli
Pictorial
Rudimentary written commands
Where is prosody processed?
Right hemisphere
What is prosody?
Emotional and tonal colouring of language
What is the effect of damage to the anterior right hemisphere?
Inappropriate intonation in speech
What is the effect of damage to the posterior right hemisphere?
Difficulty interpreting emotion in speech
What is the WADA procedure?
Short acting anaesthetic, such as sodium amytal, injected into right or left internal carotid artery, anaesthetising the ipsilateral hemisphere
Speech then assessed
Enables determination of dominant speech-processing hemisphere
What is transcortical motor aphasia?
2. Can repeat very long sentences
What is transcortical sensory aphasia?
How is the written word processed?
Which parts of the brain are activated by passively viewing words?
Striate and extra-striate cortex
Which parts of the brain are activated by listening to words?
2. Wernicke’s area