(M) Pattern of Inheritance

Question 1

T or F. The pattern of inheritance is the interaction between alleles in heterozygotes

Answer 1

T

Question 2

• one allele controls the phenotype—can already manifest
• does not skip generation

Answer 2

Dominant

Question 3

• does not control the phenotype—unless it’s homozygous or sex linked (XY)
• not expressed in heterozygotes
• neither parent is required to have the trait since they can be heterozygous (carriers) that can later on manifest to the next generation

Answer 3

recessive

Question 4

What’s the ratio of the offspring that will be affected in autosomal dominant inheritance?

Answer 4

50:50

Question 5

T or F. X linked gene is located on one of the numbered chromosome or nonsex chromosome

Answer 5

F (autosomal)

Question 6

In Autosomal Dominant, if there are 4 sons, how many will be affected?

Answer 6

2 (50%)

Question 7

This diseases such as Huntington Disease, and Neurofibromatosis mostly occur in this type of gene

Answer 7

autosomal dominant

Question 8

T or F. In autosomal dominant, MALE & FEMALE can transmit the trait to their offspring since one mutated copy of the gene in each cell is sufficient.

Answer 8

T

Question 9

T or F. There’s skipping of generation in autosomal dominant.

Answer 9

F

Question 10

Need 2 mutated copies of gene for it to manifest

Answer 10

Autosomal Recessive

Question 11

ratio of Autosomal Recessive

Answer 11

1:2:1

(HETEROZYGOUS PARENTS: 1/4 or 25% of the progeny will be affected)

Question 12

T or F. In autosomal recessive, the parents can be unaffected

Answer 12

T (kasi carrier sila, their offspring will inherit it)

Question 13

T or F. In autosomal recessive, this only appears in male.

Answer 13

F (both male and female)

Question 14

What are the diseases associated with autosomal recessive?

Answer 14

Cystic fibrosis, Albinism

Question 15

one single gene is needed for the disease to be manifested—more common in female

Answer 15

X-Linked Dominant

Question 16

This gene has no male-male transmission

Answer 16

X-linked Dominant and X linked reccesive

Question 17

T or F. Daughters are affected by their mother more than their father in X-linked dominant.

Answer 17

F (father raw then the mother affect both son and daughter)

Question 18

This gene has severe effect in male (XY) because there is no other allele to mask its effects

Answer 18

X-linked dominant

Question 19

this gene is always expressed in males than in females.

Answer 19

X-linked recessive

Question 20

T or F. The x-linked recessive is mostly expressed in heterozygous.

Answer 20

F (Rarely sa females)

Question 21

T or F. In x-linked recessive, affected sons are born to affected mother while all daughters of affected father will become carrier

Answer 21

T

Question 22

What gene is mostly associated with these diseases: Hemophilia A and G6PD

Answer 22

X-linked recessive

Question 23

AKA HOLANDRIC Inheritance

Answer 23

Y-linked recessive

Question 24

the only gene that is passed from father to all sons and does not skip generations

Answer 24

y-linked recessive

Question 25

T or F. In Y linked recessive, it does not skip generations even in females.

Answer 25

F (they only become carriers; di ko gets paano pero ayan sabi ni mam f2f pokey)

Question 26

This gene is inherited through the maternal line (egg cell)

Answer 26

mitochondrial inheritance

Question 27

T or F, in mitochondrial, male can still be infected but only daughters can pass it to their children

Answer 27

T