Microbiology Part 1 Flashcards

1
Q

Phagocytic cells of the immune system

A

neutrophils, monocytes, macrophages

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2
Q

present antigen to T cells,

starts as Monocyte

A

macrophages

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3
Q

can inactivate pathogens

A

natural killer cells

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4
Q

3 main types of T cells

A

killer T, helper T and Regulatory T

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5
Q

triggers target to commit “suicide”

A

killer T cells

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6
Q

help in antigen recognition and regulation

A

helper T cells

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7
Q

keeps other T cells under control

A

regulatory T cells

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8
Q

target of antibody and T cells

A

antigen

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9
Q

where antibody binds on antigens

A

epitope

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10
Q

present antigen for T cells to see

A

Histocompatibility Complex Proteins

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11
Q

found on surface of most cells,

iinforms Killer T cells of whats goin on INSIDE cell

A

Class 1 HCP

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12
Q

made by antigen presenting cells (macrophages), informs helper T cells of problems OUTSIDE cells

A

class 2 HCP

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13
Q

plants the “kiss of death”

A

antibody (opsonization)

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14
Q

very fast system of 20 different proteins made by the liver consisting of 3 different pathways

A

Complement system

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15
Q

3 different pathways of the Complement System

A

classical (depends of antibodies)
Alternative (antibody independnt)
Lectin activation path

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16
Q

mannose binds lectin leading to the attraction of phagocytes

A

lectin activation pathway (complement system)

17
Q

T cell mediated hypersensitivity

A

Type IV

18
Q

caused by proteins from mold or plant spores

A

hay fever

19
Q

caused by dust mites, cockroaches, rodents, and household pets

A

asthma

20
Q

allergic reponse cells that degranulate

A

mast cells

21
Q

self-reactive T cells,
myelin sheaths destroyed,
CNS

A

multiple sclerosis

22
Q

Activated T cells can cross the BBB

A

multple sclerosis

23
Q

90% women,
inflammation of lungs, arthritis, kidney damage, hair loss, paralysis and convulsions, caused by breakdown of B and T cells that make IgG antibodies

A

Lupus

24
Q

Thymic tissue missing,
Bubble boy,
No T cells

A

DiGeorge syndrome

25
Q

no T or B cells

A

Severe Combined Immunodeficiency Syndrome

26
Q

Pneumocystis carinii

A

AIDS

27
Q

Sabin

A

live and attenuated virus

28
Q

Salk

A

Kills virus

29
Q

Generates memory helper T and B cells but not memory killer T cells

A

Noninfectious vaccines (salk)

30
Q

vaccine with weakened form of microbe,

produce memory killer T cells

A

attenuated (most vaccines)

31
Q

introduces a single gene from pathogenic microbe into virus,
called a Trojan horse,
doesn’t cause disease

A

carrier vaccine

32
Q

active immunity

A

live (attenuated) or killed viruses

33
Q

passive immunity

A

occurs naturally