Antonie van Leeuwenhoek and Robert Hooke
First to observe microbes
Worked at same time, but not together
AvL looked at microbes
H looked at fungal structures (not individual cells)
Louis Pasteur (1822-1895)
The Father of Microbiology
- Biogenic Origin of Microbes (disproved spontaneous generation of life)
- Sterilization and Pasteurization
- Fermentation
Vaccines (Esp. rabies, fowl cholera and anthrax vaccine)
Edward Jenner (1749-1823)
Smallpox vaccine
Progressed vaccinations/immunology
Joseph Lister (1827-1912)
Surgeon - developed aseptic technique using phenol
Robert Koch (1843-1910)
Germ Theory of Disease
Koch’s postulates of disease
Developed solid media (agar plates) and isolated poor cultures)
Dimitri Ivanowski (1864-1920)
Discovered visuses (tobacco mosaic virus on diseased tobacco plant) in 1892
Martinus Beijerink (1851-1931)
Showed intracellular growth (that they could infect and grow inside other organisms) by viruses and microbial basis of major processes in biogeochemical cycles (e.g. nitrogen fixation)
Sergei Winogradsky (1856-1953)
Chemolithotrophy (process of microbes getting energy from inorganic compounds - S, metals etc)
Biogeochemical cycles
Alexander Fleming
1929 - Penicillin
Expanded on by Selman Waksman - discovered more antibiotics
Carl Woese (1928-2012)
Discovered Archaea - devised three domain phylogenetic tree
First to use molecular sequencing to classify organisms