Advanced Pharmacology 533 > Modules 7-8 Antibiotics > Flashcards

Modules 7-8 Antibiotics Flashcards

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1
Q

Which ABTs for mild cellulitis in the immunocompromised, DM, vasc insufficient, etc?

  • Amox/TR-Clav (Augmentin)
  • Levofloxacin + clindamycin
  • moxifloxacin
A

-

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2
Q

Which ABTs for mild cellulitis in the immunocompromised, DM, vasc insufficient, etc?

A
  • Amox/TR-Clav (Augmentin)
  • Levofloxacin + clindamycin
  • moxifloxacin
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3
Q

Which ABTs for mod-severe cellulitis in the immunocompromised, DM, vasc insufficient, etc?

A
  • Vancomycin
  • daptomycin
  • telavancin
  • linezolid +B-lactam
  • carbapenem
  • ceftaroline with clindamycin or metronidazole
  • ceftazidime with clindamycin
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4
Q

Which ABTs for mod-severe cellulitis in the immunocompromised, DM, vasc insufficient, etc?

  • Vancomycin
  • daptomycin
  • telavancin
  • linezolid +B-lactam
  • carbapenem
  • ceftaroline with clindamycin or metronidazole
  • ceftazidime with clindamycin
A

-

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5
Q

Which ABTs for mild cellulitis in previously healthy people?

  • dicloxacillin
  • cephalexin
  • clindamycin
A

-

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6
Q

Which ABTs for mild cellulitis in previously healthy people?

A
  • dicloxacillin
  • cephalexin
  • clindamycin
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7
Q

Which ABTs for mod-severe cellulitis in previously healthy people?

A
  • nafcillin
  • cefazolin
  • clindamycin
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8
Q

Which ABTs for mod-severe cellulitis in previously healthy people?

  • nafcillin
  • cefazolin
  • clindamycin
A

-

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9
Q

If CA-MRSA is suspected or there’s an allergy to PCN, treat mild cellulitis in previously healthy adults with:

  • clindamycin
  • SMZ/TMP
  • doxycycline
A

-

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10
Q

If CA-MRSA is suspected or there’s an allergy to PCN, treat mod-severe cellulitis in previously healthy adults with:

  • Vancomycin
  • linezolid
  • daptomycin
  • ceftaroline
  • telavancin

(Regarding cellulitis.)

A

-

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11
Q
  • Vancomycin
  • linezolid
  • daptomycin
  • ceftaroline
  • telavancin

What do these ABTs treat?

(Regarding cellulitis.)

A

Mod-severe cellulitis in previously healthy adults when CA-MRSA is suspected or there’s an allergy to penicillin.

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12
Q
  • clindamycin
  • SMZ/TMP
  • doxycycline

What do these ABTs treat?

(Regarding cellulitis.)

A

Mild cellulitis in previously healthy adults when CA-MRSA is suspected or there’s an allergy to penicillin.

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13
Q
  • nafcillin
  • cefazolin
  • clindamycin

What do these ABTs treat?

(Regarding cellulitis.)

A

Mod-severe cellulitis in previously healthy adults.

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14
Q
  • dicloxacillin
  • cephalexin
  • clindamycin

What do these ABTs treat?

(Regarding cellulitis.)

A

Mild cellulitis in previously healthy adults.

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15
Q

Bacterium most common causing uncomplicated cellulitis?

A

S. pyogenes (GAS)

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16
Q
  • Clindamycin
  • TMP/SMZ
  • doxycycline
  • minocycline
  • linezolid
  • tedizolid
  • delafloxacin

These ABTs treat what?

A

MRSA in adults

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17
Q

Regarding hyperse_________, avoid penicillins or cephalosporins in patients with a history of it.

A

hypersensitivity

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18
Q

Avoid these ABTs in children:

  • cycl___s
  • quino____s
A
  • cyclines
  • quinolones
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19
Q

There are drug interactions between quinol___s and Ca, Mg, iron, etc.

A

quinolones

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20
Q

If hypersensitive to an ABT like PCN, cephalosporins, and carbapenems, you can use an alter______ ABT.

A

alternative

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21
Q

Antibiotic of choice for animal bites: (Aug______)

A

Amoxicillin-Clavulanate (Augmentin)

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22
Q

An alternative antibiotic empiric regimen for animal bites. One of the 1st group and one of the 2nd group.

1st: (ONE OF THESE)
- doxycycline
- TMP/SMZ
- penicillin
- cefuroxime
- moxifloxacin

AND

2nd: (ONE OF THESE)
- metronidazole
- clindamycin

A

-

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23
Q

Is doxycycline and metronidazole OK as an alternative treatment for animal bites?

[Y/N Q]

A

Y

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24
Q

Is penicillin and clindamycin OK as an alternative treatment for animal bites?

[Y/N Q]

A

Y

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25
Metronidazole or clindamycin are OK options for the SECOND part of the alternative combination in treating animal bites.
-
26
Tetracyclines should be avoided in children.
-
27
Tetrac_______ should be avoided in children.
Tetracyclines
28
S. pyogenes and S. aureus are most commonly involved in impetigo in children.
-
29
Treatment for impetigo include: - antistaphylococcal penicillins (like dicloxacillin) - 1st gen cephalosporins (like cephalexin)
-
30
Treatment options for impetigo include: - dicloxac_____ - cephal____
- dicloxacillin - cephalexin
31
For uncomplicated LUTIs, use: - nitrofurantoin - SMZ/TMP
-
32
For uncomplicated LUTIs, use:
- nitrofurantoin - SMZ/TMP
33
For uncomplicated LUTIs, use: - nitrofur______ - SM_/TM_
- nitrofurantoin - SMZ/TMP
34
For complicated LUTIs, use: - cefpodoxime - SMZ/TMP - quinolone
-
35
For complicated LUTIs, use:
- cefpodoxime - SMZ/TMP - quinolone
36
For complicated LUTIs, use: - cefpod_____ - SM_/TM_ - quino____
- cefpodoxime - SMZ/TMP - quinolone
37
Antibiotic agents of choice for asymptomatic bacteriuria: - beta-lactams - nitrofurantoin - fosfomycin
-
38
Antibiotic agents of choice for asymptomatic bacteriuria:
- beta-lactams - nitrofurantoin - fosfomycin
39
Antibiotic agents of choice for asymptomatic bacteriuria: - beta-lact___ - nitrofur______ - fosfomy___
- beta-lactams - nitrofurantoin - fosfomycin
40
ABTs for asymptomatic bacteriuria and cystitis in pregnancy: - nitrofurantoin - amoxicillin - amoxicillin-clavulanate - cephalexin - cefpodoxime - fosfomycin - TMP/SMZ
-
41
These ABTs are for...? - nitrofurantoin - amoxicillin - amoxicillin-clavulanate - cephalexin - cefpodoxime - fosfomycin - TMP/SMZ
ABTs for asymptomatic bacteriuria and cystitis in pregnancy.
42
ABTs for asymptomatic bacteriuria and cystitis in pregnancy:
- nitrofurantoin - amoxicillin - amoxicillin-clavulanate - cephalexin - cefpodoxime - fosfomycin - TMP/SMZ
43
Don't use fosfomy___ for asymptomatic bacteriuria/cystitis IF pyelonephritis is suspected, because it does not achieve therapeutic levels in the kidneys.
Fosfomycin
44
Don't use TM_/SM_ during the first trimester or at term.
TMP/SMZ
45
Don't use nitrofuran____ during the first trimester or at term.
Nitrofurantoin
46
Don't use nitrofuran____ for asymptomatic bacteriuria/cystitis IF pyelonephritis is suspected, because it does not achieve therapeutic levels in the kidneys.
Nitrofurantoin
47
Regarding ABTs for asymptomatic bacteriuria and cystitis in pregnancy: Amoxi______ resistance may limit its utility among gram-negative pathogens.
Amoxicillin
48
For uncomplicated pyelonephritis, use: - SMZ/TMP - quinolones
-
49
For uncomplicated pyelonephritis, use:
- SMZ/TMP - quinolones
50
For uncomplicated pyelonephritis, use: - SM_/TM_ - quino_____
- SMX/TMP - quinolones
51
Primary regimen for uncomplicated bacterial prostatitis with risk of STD: 1) Ceftriaxone x1 dose OR cefixime x1 dose THEN: 2) Doxycycline BID x10 days
-
52
Primary regimen for uncomplicated bacterial prostatitis with risk of STD: 1) Ceftria____ x1 dose OR cefix___ x1 dose THEN: 2) Doxycy_____ BID x10 days
1) Ceftriaxone x1 dose OR cefixime x1 dose THEN: 2) Doxycycline BID x10 days
53
Primary regimen for uncomplicated bacterial prostatitis with risk of STD:
1) Ceftriaxone x1 dose OR cefixime x1 dose THEN: 2) Doxycycline BID x10 days
54
Primary regimen for uncomplicated bacterial prostatitis with LOW risk of STD: - Levofloxacin OR ciprofloxacin x10-14 days OR - SMZ/TMP BID x10-14 days
-
55
Primary regimen for uncomplicated bacterial prostatitis with LOW risk of STD:
- Levofloxacin OR ciprofloxacin x10-14 days OR - SMZ/TMP BID x10-14 days
56
Primary regimen for uncomplicated bacterial prostatitis with LOW risk of STD: - Levof_______ OR ciprof_______ x10-14 days OR - SM_/TM_ BID x10-14 days
- Levofloxacin OR ciprofloxacin x10-14 days OR - SMZ/TMP BID x10-14 days
57
Use of adjunctive uroselective alpha-adrenergicantagonists should be considered to reduce symptomatology of bacterial prostatitis. These symptoms include poor urinary stream, hesitancy, etc. These meds include: - tamsulosin - alfuzosin - silodosin
-
58
- tamsulosin - alfuzosin - silodosin These are adjunctive uroselective alpha-adrenergicantagonists that help with the symptoms of bacterial prostatitis (hesitancy, poor urinary stream, etc).
-
59
SMZ/TMP also known as co-trimoxazole
-
60
co-trimoxazole =
SMZ/TMP
61
SMZ/TMP =
co-trimoxazole
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