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Flashcards in Monitoring Deck (23)
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1
Q

What drug monitoring is needed on amiodarone?

A

Prior to treatment - TFT, LFT, U&E, CXR

TFT, LFT every 6 months

2
Q

When do you alter the thyroxine dose following TFTs?

A

TSH level
< 0.5 = decrease dose

0.5-5 = same dose

> 5 = increase dose

3
Q

When do you monitor gentamicin levels?

A

6-14h post infusion.
This is then plotted on a normogram.
If too high dose is taken every 36 or 48 hours rather than the regular 24.

4
Q

When is the peak and trough measured with gentamicin?

A

Peak 1 hr post dose (too high =adjust dose)

Trough just before next dose (too high = adjust interval)

5
Q

When is kidney function measured in someone with CKD after starting a ACEi?

A

1-2weeks following initiation

6
Q

What is monitored with statins and when?

A

LFT

Baseline, 3 month and 12 m.

7
Q

What is monitored in sodium valproate?

A

LFT

LFT and FBC baseline, then LFT periodically in first 6ms

8
Q

What is monitored in Lithium?

A

Lithium level - weekly until stable then every 3 months

TFT and u and e at baseline and every 6 m

9
Q

How do you monitor effectiveness of furosemide treatment?

A

Weight reduction

10
Q

How to monitor beneficial effects of heart failure treatment?

A

Improved exercise tolerance

11
Q

What needs to be monitored in cyclosporine treatment,?

A

First 2 weeks - Nephrotoxicity - monitor renal function eg creatinine

Later - liver function too - monthly

12
Q

What should be checked prior to starting someone on simvastatin?

A

Liver function tests (AST and ALT), contraindicated in poor hepatic function as its metabolised by the liver and could increase levels leading to myopathy.

13
Q

When is the lithium level checked after the dose?

A

12hours

14
Q

Which electrolyte abnormality increases the risk of lithium toxicity?

A

Sodium depletion

15
Q

When to check FBC in methotrexate treatment?

A

Every 2-3 months

16
Q

How is methotrexate excreted?

A

Renally (more toxicity in renal failure)

17
Q

What needs to be checked prior to starting olanzipine?

A

Fasting blood glucose.

ECG - if have cardiovascular disease

18
Q

What should be checked prior to amiodarone treatment?

A

Chest X-ray (due to pulmonary toxicity)

LFT ( at regular intervals)
Cautioned in patients with hypokalaemia

19
Q

What should be monitored during treatment in digoxin?

A

Renal functions (creatinine)

And k+, as hypokalemia increases risk of digoxin toxicty.

20
Q

What needs to be checked prior to starting sodium valproate treatment?

A

Liver function tests (ALT) as can cause hepatotoxicity

21
Q

How is clozapine monitored?

A

FBC every week, for first 18 weeks of treatment. And must register with a clozapine monitoring service. Stop the drug if any signs of neutropenia.

22
Q

What monitoring is required in IV phenytoin administration?

A

ECG as cardiac arrhythmias

23
Q

What’s the treatment for low warfarin INR levels?

A

Increase the dose (and cover for the time it will take to work with a quick acting anticoagulant eg LMWH.)