Multiple Dosage Forms Part 2

Question 1

What is intermittent infusion?

Answer 1

1. Method of successive short IV drug infusions in which the drug is given by IV infusion for a short period of time followed by a drug elimination period, then followed by another short IV infusion

Question 2

What is the rationale for intermittent IV infusion?

Answer 2

To prevent transient high drug concentrations and accompanying side effect

May or may not reach steady state

Question 3

What equation do we use for intermittent infusion?

Answer 3

Question 4

What equation do we use when intermittent infusion has stopped?

Answer 4