Narcan

Question 1

Naloxone Class

Answer 1

Competitive narcotic agonist, antidote (B)

Question 2

Naloxone Indications

Answer 2

1. Known or suspected narcotic overdose with respiratory rate less than 8
2. Decreased tidal volume
3. Decreased minute volume (pupil constriction is key finding)

Question 3

Naloxone Mechanism

Answer 3

Competes with narcotics at opiate receptor site in the CNS to reverse the effects of certain narcotic analgesics

Question 4

Naloxone Side Effects

Answer 4

• Nausea
• Vomiting
• Tachycardia
• Hypertension
• Withdrawal
• Anger
• Tremors
• Dysrhythmias
• Seizures.

Question 5

Naloxone Contraindications

Answer 5

Hypersensitivity

Question 6

Naloxone Precautions

Answer 6

1. Titrate dosage to respiratory rate and tidal volume
2. Administrator prior to ET tube
3. Monitor blood pressure (will not reverse narcotic-hypotension)
4. Nausea/Vomiting may occure if given too quickly
5. Seizures and withdrawal symptoms may occur if pts dependent on narcotics

Question 7

Naloxone Interactions

Answer 7

Narcotics often have a longer duration and may rebind to opiate receptor sites causing secondary CNS depression

Question 8

Naloxone Routes

Answer 8

IV, IO, IM, IN, SC

Question 9

Naloxone Onset

Answer 9

Within 2 minutes

Question 10

Naloxone Duration

Answer 10

30-60 Minutes

Question 11

Naloxone Adult Dose

Answer 11

0.4-2 mg, q 5 min PRN. Max dose 10 mg

Question 12

Naloxone Pedi Dose

Answer 12

0.1 mg/kg, q 5 min PRN. Max dose 10 mg