Organic Pathways - Aromatic

Question 1

Benzene to ketone

Answer 1

Acyl chloride in the presence of anhydrous AlCl3 catalyst
Electrosub

Question 2

Ketone to alcohol

Answer 2

NaBH4
Nuc.add

Question 3

Benzene to nitrobenzene (NO2)

Answer 3

Conc HNO3
Conc H2SO4
ElectroSub
55C°

Question 4

nitrobenzene (NO2) to aminobenzene (NH2)

Answer 4

Sn and HCl
Reduction

Question 5

Why would you choose the route that only produces one product

Answer 5

• multiple products can be difficult to separate and result in lower yields

Question 6

Why would you choose the route that has a higher atom economy

Answer 6

Less waste

Question 7

Why would you choose the route that has fewer steps

Answer 7

Higher yields

Question 8

Why would you choose the route that needs no/less solvents

Answer 8

• solvents can be toxic/dangerous
• it can be difficult/expensive to dispose of them