psychosis
difficulty in perceiving and interpreting reality
- symptom not a condition
what are organic psychosis causes?
a variety of conditions including strokes, brain injury, encephalitis, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, temporal lobe epilepsy or brain tumours.
Functional psychoses include schizophrenia and mood disorders such as manic-depression.
types of symptoms in psychosis
types of positive symptoms
what are delusions?
Give some examples
beliefs with lie outside of normal social or cultural beliefs
types of negative symptoms
disorganisation symptoms
- bizarre behaviour
peak age of incidence of schiz
adolescence/early 20s -> peak later in women
course of schiz
- -> very variable
how many years of life is lost in schiz?
15 years
- also 28% of excess mortality due to suicide
the psych history
what type of psychological symptoms should you check for in psychosis?
prodromal symptoms
management of psychotic disorders
which NT system is most implicated in the mechanism of antipyschotics
Extrapyramidal side effects of dopamine blockers?
What can we also call these side effects?
Parkinson’s syndrome side effects:
acute dystonia
tardive dyskinesia
akathisia
what is dystonia
motor tone is increased; abnormal postures. If affects larynx it can be fatal.
tardive dyskinesia
akathisia
typical antipsychotics cause what?
- definition isn’t based on pharmacological drug target
other examples of side effects of antipsychotics (typical and atypical)?
Describe what bizarre behavior might include
• Bizarre social behaviour • Bizarre clothing/appearance • Aggression/agitation • Repetitive/sterotyped behaviours
Describe what though disorder may include
Derailment Circumstantial speech • Pressured speech • Distractibility • Incoherent/illogical speech
What is the impact of psychosis on morbidity?
Substantial from the disorder itself and increased risk of common health problems e.g. heart disease
Impact on education, employment and functioning
What is the impact of psychosis on mortality?
2.5 times all cause mortality
15 years expected life loss
Highest risk of suicide in schiz (28%)