What do long-current stimulations reveal about PMC outputs?
They elicit complex, natural, species-typical movement sequences rather than single muscle contractions (e.g., reaching, grasping, bringing food to the mouth).
How is the somatotopic organization of PMC viewed currently?
Looser than previously thought; stimulation sites overlap across body parts, and movements are complex rather than isolated muscle contractions.
What does overlap in PMC stimulation sites explain?
Why small lesions in areas like the hand region do not selectively disrupt a single finger’s activity.
What evidence supports the endpoint/goal coding of PMC neurons?
Studies in freely moving monkeys show neurons fire when reaching a specific location, independent of the trajectory taken.
What are the three main sources of input to the cerebellum?
Primary and secondary motor cortex, Brainstem motor nuclei, Somatosensory and vestibular feedback
What is the main function of the cerebellum?
While movement is initiated, the cerebellum is responsible for a quality check of the movement.
- Cerebellum will give you an alternate plan to keep you from deviating form the target.
What role does the cerebellum play in motor learning?
It helps in learning and refining movement, especially those that require precise timing.
What happens when the cerebellum is damaged?
Loss of coordination, inaccurate movements, tremors, poor balance, speech and eye movement problems, and difficulty learning new motor skills.
What was the older view of cerebellar function and what is the modern view now?
That it was purely for motor control (sensorimotor).
Now: It also contributes to sensory, cognitive, emotional, and memory processing.
What theory explains the cerebellum’s role in learning?
The cerebellum helps learn from errors and predict future errors.
Give an example of cerebellar function in everyday life.
excercise machine that changes speed in each leg.
Why is the cerebellum considered functionally complex?
Because of its dense neuron count and extensive connectivity with other brain regions.
How is the structure of the basal ganglia different from the cerebellum?
The basal ganglia are irregular and not organized into lobes or layers like the cerebellum.
Do the basal ganglia send direct signals to muscles?
No — they influence movement indirectly through loops that connect with the cortex and cerebellum.
What are the functions of the basal ganglia?
What types of learning involve the basal ganglia?
Habit learning (gradual, trial-by-trial learning) and classical conditioning (learning through association).
What are the two main roles of the basal ganglia in sensorimotor function?
Movement vigor — controlling the speed and force of movement.
Movement inhibition— suppressing unwanted or inappropriate movements.
(Example: resisting the urge to yawn or scratch in public.)
What happens if the basal ganglia fail to inhibit unwanted movement?
It can lead to motor or psychiatric symptoms, such as tremors, tics, or compulsive behaviors.
What neurological disorders are linked to basal ganglia dysfunction?
Parkinson’s disease , Huntington’s disease and tourette’s.
What do the basal ganglia and cerebellum have in common?
Both modulate movement and form loops with cortical motor areas.
What are the two main types of descending motor pathways, and what do they have in common?
Types:
* Dorsolateral pathways
* Ventromedial pathways
Common features:
How do dorsolateral and ventromedial pathways differ in their synaptic connections?
Dorsolateral:
Ventromedial:
What muscles do the dorsolateral and ventromedial tracts control?
Dorsolateral:
Controls distal muscles (hands, fingers, face, toes)
Ventromedial:
Controls proximal muscles (trunk, shoulders, hips