Likelihood Ratio
LR = Sensitivity /(1- Specificity)
Post-test odd =
Pre-test odd x likelihood ratio (LR)
Prevalence =
incidence x duration
Power =
1 – the probability of a type II error
The rapid COVID test has a sensitivity of 90% and specificity of 99%. If the prevalence of
COVID is 1 in 100, what is the approximate positive predictive value of the rapid COVID
test?
50%
relative risk
EER / CER
Experimental event rate, EER
CER, Control event rate
In a cohort study, the usual outcome measure is
Relative Risk
Attrition Bias
a type of selection bias due to systematic differences between study groups in the number and the way participants are lost from a study
Systematic Error vs Sampling Bias
Systematic bias is a consistent error that skews a sample in one direction, making it unrepresentative due to flaws in the sampling method, while sampling error is the random variation that occurs simply because a sample is used to estimate a population.
variance vs coefficient of variation
Variance:
Average of squared deviations from mean
Measures absolute variability (spread of data)
Coefficient of variance:
Measures relative variability (spread compared to mean)
CV = SD/mean * 100
Standard Error of the mean
a measure of how much the sample mean is likely to differ from the true population mean
= SD/ square root (number of population)
Confidence interval calculation
Range likely containing true population value (CI = mean +/- 1.96 * SEM)
How to reduce random error
Increasing sample size (random error is caused by chance)
Prevalence vs incidence calculation
Prevalence = Existing cases/total population
Incidence = New cases/population at risk per time
Odds to probability conversion
Odds = (probability / (1 - probability)
Probability =
(Odds / ( 1+ odds)
Prognostic vs predictive
Prognostic = disease recurrence, survival
Predictive = response to therapy
Relative risk reduction calculation
Framing effect
Definition: Decisions or interpretations are influenced by how information is presented, even if the underlying facts are the same.
Attribution bias
Definition: Explaining people’s behavior based on personal traits rather than situational factors.