Week 1 maternal and fetal part 4 of 4 Flashcards Preview

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Flashcards in Week 1 maternal and fetal part 4 of 4 Deck (60)
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31

how does the fetus produce heat

by burning brown fat

32

maintain room temp at

26c

33

fetal development 3rd week- nucleated RBC's formed where?

nucleated RBC's formed in yolk sac and mesothelium of placenta

34

fetal development 4 weeks
non - nucleated RBC's formed

formed by fetal mesenchymal and endothelial cells.

35

at 6 weeks blood cells are formed where?

liver forms blood cells

36

at 12 weeks. what happens to RBC development

spleen and lymphoid tissue, also bone marrow: red and white blood cells, other structures lose ability to form blood cells.

37

diffusion through placental membrane

simple diffusion from sinuses through villus membrane down pressure gradient to fetus

38

simple diffusion from sinuses through villus membrane down pressure gradient to fetus

mean p02 in fetal blood pressure

30mmhg

39

simple diffusion from sinuses through villus membrane down pressure gradient to fetus

mean p02 in villus

50mmhg

40

simple diffusion from sinuses through villus membrane down pressure gradient to fetus

from maternal blood pressure

100mmhg

41

what is the fetal Hb affinity for 02

very high affinity

42

fetal Hb can carry how much more 02 % than maternal Hgb

20-30% more 02

43

which way does newborn oxygen-hb curve shift

left shift

44

fetal Hb concentration in blood is what % greater than in mother

50%

45

anemia when Hb< ___ newborn

13

10- g/dl in >3mos

46

name the two ways nutrients go from mother to fetus

similar to oxygen- higher to low gradient

electrochemical gradients.

47

CO2 builds up until it is slightly higher in fetus umbilical arteries (___mmhg)

48mmhg

48

co2 is higher in fetus umbilical arteries at 48mmhg than in intervillous space (___mmhg)

43mmhg

49

fetal affinity for co2

affinity for c02 is lower in fetus- favoring transfer from fetus to mother

50

receptor mediated endocytosis from mother:

LDL

(what does this mean)

51

renin increases late in gestation due to what three things

Renal sympathetic nerve activity

Reduction in Na and blood volume

Change in renal perfusion pressure

52

fetal GFR and concentrating ability

low GFR
Low Concentrating ability

53

due to decrease GFR and decrease concentrating ability can the fetus tolerated volume overload

no they cannot tolerate volume overload.

54

fetal aldosterone level?

low, rapid clearance

55

angiotensin II not directly related to

renin (LOW ACE, HIGH CLEARANCE)

56

noninvasive diagnosis of fetal well being

transvaginal ultrasound: visualize vertebrae, kidneys, bladder, fingers and toes by 12 wks gestation

57

invasive diagnosis of fetal well being

amniocentesis
14-16 weeks: when amniotic cavity contains 150-200ml remove 20ml; with simultaneous ultrasound karyotyping, biochemical analyses, dna

58

diagnosis of fetal well being
Chorionic villus sampling

cytogenetic and biochemical testing recommended after 10 wks gestation; usually 2nd and 3rd trimester

59

Chorionic villus sampling - when is this testing recommended

recommended after 10 wks gestation, usually 2nd and 3rd trimester

60

diagnosis of fetal well being
Fetal blood sampling

transabdominal; from 17 wks into umbilical vein about 1 cm from placental cord insertion site