Week 3 pregnancy & lactation (everything) Flashcards Preview

SUM'20 - Advanced Principles > Week 3 pregnancy & lactation (everything) > Flashcards

Flashcards in Week 3 pregnancy & lactation (everything) Deck (125)
Loading flashcards...
31

**exam-
what analgesic drug do we avoid in the third trimester?

Aspirin

32

**exam-
why do we avoid aspirin in the third trimester of pregnancy?
name 3 injuries that occur

Renal injury
Oligohydramnios
Intrauterine constriction of the ductus arteriosus

33

**exam
what do we know about opioids and their teratogenic risk

NO teratogenic risk!

34

**exam-
tramadol has analgesic effects from weak opioid activity and inhibition of serotonin and norepinephrine uptake- when do we avoid it and why>

early pregnancy- associated with high number of spontaneous abortions

avoid during first trimester

35

Describe Ebsteins anomaly-

is a rare heart defect in which the tricuspid valve — the valve between the upper right chamber (right atrium) and the lower right chamber (right ventricle) of the heart — isn't formed properly.

36

**exam- lithium therapy has a small increased risk for what two condition

cardiac defects- especially ebsteins anomaly

37

**exam what specific diuretic should be avoided

spironolactone

38

**which antihypertensive drugs are safe during pregnancy

methyldopa
labetalol
calcium entry blocking agents
hydralazine

39

**which respiratory drug is not recommended? I checked it was withdrawn with US market!

Zileuton

40

**name the preferred short acting beta 2 receptor agonist

albuterol

41

**name the preferred long acting beta 2 adrenergic agonist

salmeterol

42

**pregnant women have 5 times the normal risk for what condition

venous thromboembolism and thrombosis and is a significant cause of maternal death

43

**do heparins cross the placenta

NO

44

**what is the preferred anticoagulant to give mothers

low molecular weight heparin
preferred over
unfractionated heparin

easy to administer and does not require monitoring

45

**LMWH is less likely to cause what condition

HIT- heparin induced thrombocytopenia

46

why isn't rivaroxaban and dagibatran recommended

it crosses the placenta

47

**what does the american college of obstetricians and gynecologists recommend for the initial drug for nausea

B6-pyridoxine

with or w/o doxylamine

48

**what medication has been used for refractory vomiting during pregnancy

ondansetron (5-hydroxytryptamine receptor antagonist)

49

**there is debate over which anti-diabetic should be first line drug choice. what medications are considered safe (3)

insulin
metformin
glyburide

50

**what anti-infective drug is considered safe but some recommend avoiding during first trimester

metronidazole

51

**what is the first line anti infective drug used pregnant women

penicillins and cephalosporins

52

**where should pregnant women avoid traveling

malaria endemic areas

53

**if a pregant women travels to malaria endemic area what meds can be used

chloroquine

mefloquine

54

**what are the effects of caffeine

no evidence of teratogenic affects in humans

55

**what are the effects of cannabis

no effects- but dont take it because of the adverse effects of smoking

56

**what are the risks of nicotine replacement- e cigarettes and vaping

unknown

57

**HIGHLY teratogenic drug

thalidomide, ribavirin, isotretinoin, acitretin, valproate

58

highly teratogenic drugs additional recommendations

So high risk of teratogenic- use two forms of BC

59

do anticonvulsants cross the placenta

yes- all of them

60

do the offspring of anti epileptic patients has a propensity to develop epilopsy

yes