Motor Neurone DISEASE

Question 1

Is it UMN or LMN that are usually more affected in MND

Answer 1

90% LMN

Question 2

Which is the MND variation that affects UMN

Answer 2

Primary Lateral Sclerosis

Question 3

List other variants on MND

Answer 3

Flail arm syndrome
Flail leg syndrome
Primary Lateral Sclerosis

Focal distal spinal muscular dystrophy
Kennedy’s disease (SMA variant)

Question 4

with regards to diagnosis which regions are taken into account and how many do you need for a diagnosis

Answer 4

bulbar thoracic upper lim lower
limb
3 for definte
2 for porbable
1 possible

Question 5

what are the UMN signs?

Answer 5

Spasticity
Babinski sign
Bulbar UMN signs: exaggerated snout reflex, clonic jaw jerk, emotional lability, forced jawning
Cervical and lumbar region: Clonic deep tendon reflexes, preserved reflex in a weak, wasted limb, Hoffmann reflex, hyperreflexia
Abdominal region: loss of superficial abdominal reflexes