Alzheimers Dementia Flashcards

1
Q

Aetiologies?

A

Environmental and genetic causes

RF: strong FH, down syndrome, Vascular RF, alcoholism, smoking

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2
Q

Pathology?

A

Selective neuronal loss in the cortex

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3
Q

Signs and Symptoms?

A

Main initial domains of neuronal loss: spatial awareness, self awareness, memory, higher function, verbal
Progresses into intellect/behavioural/psychotic decline

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4
Q

Investigations and Findings?

A

Diagnosis purely clinical

Excludatory investigations

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5
Q

Management?

A

No definitive cure
MDT based support for family and patient
Acetylcholinesterase inhibitors = symptomatic, BP control

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6
Q

Complications?

A

Progressive decline into sedation

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