34: Toxicology and Substance Abuse Flashcards

0
Q

Any chemical (drug, poison, or other) that causes adverse effects on an organism.

A

Toxin

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1
Q

Study of the detection, chemistry, pharmacological actions, and antidotes of toxic substances.

A

Toxicology

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2
Q

Entry of a substance into the body through the respiratory tract.

A

Inhalation

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3
Q

Entry of a substance into the body directly through the skin or mucous membrane.

A

Surface Absorption

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4
Q

Phosphorus-containing organic chemicals.

A

Organophosphates

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5
Q

Entry of a substance into the body through a break in the skin.

A

Injection

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6
Q

The process of minimizing toxicity by reducing the amount of toxin absorbed into the body.

A

Decontamination

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7
Q

Removing an ingested poison by reportedly filling and emptying the stomach with water or saline via a gastric tube; also known as “pumping the stomach”.

A

Gastric Lavage

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8
Q

A powder, usually premixed with water, that will absorb some poisons and help prevent them from being absorbed by the body.

A

Activated Charcoal

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9
Q

Administration of polyethylene glycol continuously at 1-2 L/Hr through a nasogastric tube until the effluent is clear or objects are recovered.

A

Whole bowel irrigation

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10
Q

A substance that will neutralize a specific toxin or counteract its effect on the body.

A

Antidote

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11
Q

A toxic sydrome; a group of typical signs and symptoms consistently associated with exposure to a particular type of toxin.

A

Toxidrome

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12
Q

A substance that liberates hydrogen ions when in solution.

A

Acid

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13
Q

A substance that liberates hydoxyl ions when in solution; a strong base.

A

Alkali

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14
Q

The maximum tolerated dose divided by the minimum curative dose of a drug; the range between curative and toxic dosages; also called therapeutic window.

A

Therapeutic Index

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15
Q

A soluble poisonous substance secreted during growth of a bacterium.

A

Exotoxin

16
Q

An exotoxin that produces gastrointestinal symptoms adn diseases such as food poisoning.

A

enterotoxin

17
Q

Poisoning from a pharmacological substance in excess of that usually prescribed of that the body can tolerate.

A

Drug overdose

18
Q

Use of a pharmacological substance for purposes other than medically defined reasons.

A

Substance abuse

19
Q

Compulsive and overwhelming dependence on a drug, physiological dependence, a psychological dependence, or both.

A

Addiction

20
Q

The need to progressively increase the dose of a drug to reproduce the defect originally achieved by smaller doses.

A

Tolerance

21
Q

Referring to alcohol or drugs. In which the patient’s body reacts severely when deprived of the abused substance.

A

Withdrawal

22
Q

Disorder found in habitual and excessive users of alcoholic beverages after cessation of drinking for 48-72 Hrs. Patients experience visual, tactile, and auditory disturbances, Death may result in severe cases.

A

Delirium Tremens (DTs)