Antibiotic drugs, moa, coverage Flashcards Preview

PT3 ID 1 (HIV) > Antibiotic drugs, moa, coverage > Flashcards

Flashcards in Antibiotic drugs, moa, coverage Deck (40)
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1

Penicillin G

IV (no e- withdrawing group)
streptococcus, NEVER staph

2

Penicillin v/k

oral
streptococcus, NEVER staph

3

Oxacillins

oral
staph only

4

nafcillin

staph only

5

ampicillin

gram+
susceptible to beta-lactamase

6

amoxicillin

gram+
susceptible to beta-lactamase

7

ticarcillin

gram-
pseudomonas

8

piperacillin

good gram -/+
pseudomonas
enterococci
anaerobes

9

imipenem/meropenem

some gram+
broad gram-
pseudomonas

10

ertapenem

some gram+
broad gram-
NO pseudomonas, enterococcus, acinetobacter

11

aztreonam

gram-
enterobacteriacea
pseudomonas

12

beta lactam drugs

penicillins
penems
aztreonam
cephalosporins
clavams

13

1st gen cephalosporins

cephalexin
cefazolin
cefadroxil

14

1st gen cephalosporin coverage

broad gram+
no MRSA

15

2nd gen cephalosporins

cefuroxime
cefoxitin
cefproxil

16

2nd gen cephalosporin coverage

broad gram+
some e. coli and klebsiella

17

3rd gen cephalosporins

ceftriaxone
cefixime
cefpodoxime
cefdinir
cefotaxime
ceftazidime

18

3rd gen cephalosporin coverage

some gram+
good for gram- besides pseudomonas

19

3rd gen cephalosporin with pseudomonas coverage

ceftazidime

20

4th gen cephalosporin

cefepime

21

4th gen cephalosporin coverage

some gram+
good gram- including pseudomonas
no anaerobes

22

vancomycin

glycopeptide
great gram+
MRSA
C. diff

23

quinolones

ciprofloxacin
levofloxacin
moxifloxacin

24

quinnolones moa

dna gyrase inhibitor

25

quinolone coverage

good gram-
cipro pseudomonas
moxi anaerobes
levo best gram+

26

trimethoprim moa

inhibits tetrahydrofolic acid production

27

sulfamethoxazole moa

inhibits dihydropteroic acid production

28

tetracyclines moa

ribosome inhibitors at 30s

29

tetracyclines coverage

good gm+
active against MRSA
tigecycline active against VRE/anaerobes

30

macrolides

erythromycin
clarithromycin
azithromycin