Atropine vs. ACh

Question 1

4 primary effects of ACh

Answer 1

1. vasodilation (***through NO, not direct innervation)
2. decreased HR
3. decreased AV node conduction
4. decreased force of atrial contraction (negative inotropic effect)

Question 2

Atropine main Heart effects

Answer 2

ALTERS HR!
Low levels…decrease HR (b/c block presynaptic M1 receptors so inc. ACh initially)

High levels…Increase HR

Question 3

Atropine main vascular effects

Answer 3

Atropine flush…

Question 4

Atropine utility

Answer 4

POST MI!! (to prevent severe bradycardia)

Abolishes reflex vagal cardiac slowing or asystole

Prevents or abolishes bradycardia from…

Facilitates AV conduction