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Flashcards in Cancer Of Unknown Primary Deck (11):
0

What proportion of cancers have an unknown primary?

10% following standard investigations
3% following thorough investigations

1

What cancers commonly metastasise to the liver?

Colon, lung, breast

2

What cancers commonly metastasise to the lung?

Breast, lung, kidney

3

What cancers commonly metastasise to the brain?

Lung
Breast
Melanoma

4

What cancers commonly metastasise to the bone

Breast
Bronchus
Kidney
Prostate
Thyroid

5

What cancers commonly metastasise to the peritoneum?

Ovary
Colon
Pancreas

6

Which cancers metastasise to the following lymph nodes: high cervical, supraclavicular, axillary, inguinal?

High cervical- H+N, thyroid, lung
Supraclavicular- H+N, lung, breast, GI
Axillary- breast, lung, melanoma
Inguinal- ovary, prostate, anorectal

7

What histology do most cancers of unknown primary demonstrate?

Adenocarcinoma- often from GI, breast, ovary, lung

8

What cancers cause cancer of unknown primary with a squamous cell histology?

Lung, head and neck

9

What is the management of cancer of unknown origin?

Epirubicin and cisplatin to cover most chemo responsive tumours

5fu for GI tumours

Radiotherapy for palliation/ Debulking

10

Prognosis of cancer of unknown origin?

Poor
Five year survival is less than 10%