Chapter 75 - blood purification for intoxications and drug overdose

Question 1

what are the two main mechanisms of solute removal in renal replacement therapy?

Answer 1

diffusion, convection (aka ultrafiltration)

Question 2

describe diffusion in the context of renal replacement therapy

Answer 2

movement of solute across a semi-permeable membrane driven by transmembrane concentration gradient

Question 3

describe convection (or ultrafiltration) in the context of renal replacement therapy

Answer 3

movement of water and resultant solvent drag occurring over a permeable membrane due to the transmembrane pressure gradient

Question 4

which mechanism of solute removal works better for small molecules?

Answer 4

diffusion

Question 5

which mechanism of solute removal works better for large molecules?

Answer 5

convection