How many mL of oxygen may be bound to one gram of normal Hb?
O2 unloaded (mL/dL) = Flow x Hb CONCENTRATION (g/dL)*1.34 mL O2/g x (Asat - Vsat)
How long does it take to make new erythrocytes in response to EPO?
Days to weeks
Why is administering 2,3-BPG IV no good?
It can't get into the erythrocytes!
Carbon monoxide affects ____ first
Carbon monoxide affects the heart first
Because it extracts a larger portion of available oxygen from its blood supply
Why can't carbon monoxide be picked up by a pulse oximeter?
It produces a very similar change in absorptive wavelength when bound to hemoglobin.
CO effects on hemoglobin
CO causes a left shift which decreases the ability of Hb to release its oxygen
Symptoms of CO poisoning
Tightness across forehead
Treatment for CO poisoning
Hyperbaric 100% oxygen and removal of the CO source.