Common Bacterial and Fungal Infection of the Skin Flashcards Preview

OS 212 DERMATOLOGY > Common Bacterial and Fungal Infection of the Skin > Flashcards

Flashcards in Common Bacterial and Fungal Infection of the Skin Deck (42):
1

Gram (+) cocci
Arranged in clusters
Most Pathogenic of all Staphylococci
Coagulase(+)
Catalase (+)
Has PROTEIN A (antiphagocytic)
beta hemolysis on BAP

Staphylococcus Aureus

2

Superficial inflammation of hair follicles.
Small Erythematous papules/pustules associtaed with follicles

Folliculitis

3

Commonly known as boil
Deeper form of folliculitis
Resolves upon spontaneous drainage

Furuncle

4

When furuncles coalesce
Found in thick skin
May be seen in diabetic patients

Carbuncles

5

Also called as ACNE INVERSA
disorder of the apocrine glands
Chronic disorder
Extensive scarrin, with multiple sinuses in and around the axilla

Hidradenitis Suppurutiva

6

Yellowish crust on the skin

Impetigo

7

Also called as ritter's disease or pemphigus neonatorum
Generalized skin manifestation
Most aggressive form of Staphylococcal infection
The production of exfolatin by bacteria causues this syndrome

Staphylococcal Scalded Skin Syndrome

8

Laboratory Dx of S. aureus

Gram stain: (+)
BAP and MSA
Coagulase and Catalase (+)

9

treatment of S. aureus

Penicillin

or Vancomycin

10

G(+) cocci in chains
Strict Parasite
Man is the only significant reservoir
Commonly presents as sore throat
Most serious Streptococcal pathogen
Sensitive bacitracin
Beta Hemolytic

Streptococcus pyogenes (Group A)

11

The only significant reservoir for s. pyogenes

Man (nasopharyngeal)

12

transmission of S. pyogenes

Direct/droplet

13

Non infectious sequelae of S. pyogenes

RHD, AGN

14

Impetigo in S. pyogenes

with yellow crusting

15

Infection of epidermis which extends to the dermis, with characteristic "punched" out lesions

Ecthyma

16

Shiny, swollen, red and painful
May become bullous
treated with 1st Gen cephalosporin

Cellulitis

17

Deep seated infection
Emergency case
Violaceous discoloration of the skin
Swelling within 24-48 hours, acute infection
Lesions darken; 4th-5th day then becomes gangrenous

Necrotizing Fascitis

18

Organisms associtaed with Nec Fas

peptostreptococci, Bacteroides, gram (-) rods and streptococcus

19

Laboratory Dx of Streptococcus

G(+) cocci in chains
B-hemolysis
Bacitracin Sensitive (0.02 ug)
Screening Test: Latex Agglutination (Ig monoclonal to C- carbohydrate)

20

Treatment for Streptococcus

Penicillin (cell wall inhibitors)

Low resistance against PEN (Benzathine Penicillin, Pen G or Pen V)

Alternative: Macrolides (Erythromycin)

21

Hansen's disease
Acid fast Bacillus
Cannot be cultured in vitro

Mycobacterium leprae

22

M. Leprae can be propagated in

Nude mice (no T cells)
Monkey
9-banded armadillo

23

Frequently affected nerves in Hansen's disease

Median, Radial, ulnar, Popliteal, Perineal

24

Paucibacillary

Strong CMIR
HIR normal
granuloma formation
Anesthetic
Not Infectious
treatment: 9 months

25

Multibacillary

CMIR is weak (anergy)
HIR Over reactive leads - Erythema nodosum leprossum
No granuloma
Infectious
treatment : 3 years

26

Signs and Symptoms of Hansen's disease

Area of discoloration
Anesthesia
Loss of hair in affected skin
No sweating in the area
Thickened nerve
Area not pruritic
Muscle Weakness

27

treatment for Hansen's disease

Dapsone
Rifampicin
Clofaximine - darkening of the skin

28

G(-) aerobic bacilli
opportunistic pathogen
grape like or tortilla odor in vitro
Oxidase (+)

Pseudomonas Aeruginosa

29

Definitive Diagnosis of p. Aeruginosa

Pyocyanin and fluorescein
Ability to grow at 42 degrees

30

Paronychial infection that develop in individuals whose hands are frequently submerged in water

Green Nail syndrome

31

occur in patients with decubitus ulcer, eczema and tinea pedis. These infections may have a Characteristic blue-green exudate and fruity odor

Secondary wound infections

32

Pruritic follicular, maculopapular, vesicular or pustular lesions on any part of the body that was immersed in water

HOT TUB or swimming pool folliculitis

33

Pseudomonal bacteremia produces well-recognized but uncommon distinctive skin lesion

Hemorrhagic vesicles and pustules that evolve into necrotic ulcers

Ecthyma gangrenosum

34

Treatment for P. aeruginosa

Double antibiotic therapy

Surgical removal of eschars, debridement of necrotic tissue, or in severe cases, amputaion may be required

35

Causative agent for Fish tank granuloma

M. marinum

36

Skin abscesses at the site of self administered insulin injections n the thigh of a diabetic patient

M. chelonae

37

tropical Ulcer

Fusobacterium fusiformis

38

Gram(+) rod
spore forming

Skin infection with marked necrosis and edema of tissue

Bacillus anthracis

39

Gas gangrene

Clostridium perfringens

40

Animal bite infection

Pasteurella multicoda

41

Anthrophilic fungus and is the most common and widely distributed dermatophyte of humans

Trichophytum rubrum

42

Common saprophytic fungus believed to occur in soil, compost, humus, and on wood in humid tropical and subtropical regions. Familial spread of infection is reported

Tinea Nigra