Depression Flashcards Preview

PY5030 CNS and Mental health > Depression > Flashcards

Flashcards in Depression Deck (11)
1

Different types of depression

Unipolar depression
Bipolar depression
Depressive disorder
Major depressive disorder
Dysthmia

2

Unipolar depression

Mood swings in one direction
Most common
More likely to be environmental than genetic

3

Bipolar depression

Oscillations between depression and mania
Onset happens in adulthood
Strong hereditary tendency

4

Depressive disorder

Significant levels of sadness, low energy, low self worth, guilt

5

Major depressive disorder

Severe pattern of depression, disabling, not caused by drugs or medical conditions

6

Dysthmia

Chronic and less disabling but similar to major depressive disorder

7

Ways to diagnose depression

1. Interview
2. Fill out a questionnaire
Score given tells you whether mild, moderate or severe
3. DSM diagnostic statistical manual - need to have five or more symptoms that have been present for two week period

8

Symptoms of depression

1. Depressed mood
2. Loss of interest/pleasure
3. Weigh loss/gain; increase/decrease in appetite
4. Insomnia/hypersomnia
5. Psychomotor agitation or retardation
6. Fatigue/loss of energy
7. Feeling of worthlessness or guilt
8. Less able to concentrate/think, indecisiveness
9. Recurrent thoughts of death
10. Loss of libido

- Need atleast 1 or 2 to be diagnosed with depression
- Need tohave five or more symptoms present for TWO week period

9

Factors affecting depression

- More likely in female
- First episode occurs in late adolescent early adulthood years
- May be co-morbid with other psychiatric disorders
- Causes hyperactivity of prefrontal cortex

10

Monoamine theory of depression

- Overall reduction in central monoamine NT i.e. 5-HT and NA

11

Evidence against monoamine theory of depression

- Difficult to show deficits of 5-HT and NA
- Would expects effects to be exhibited immediately but takes two-three weeks to show effects
- Cocaine blocks monoamine transporters so you'd expect it to have anti-depressive effects but it doesn't