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Flashcards in Diabetes Deck (4):
1

What autoantibodies are found in Type 1 DM

ICA: Islet cell antibody, detectable years before disease onset.
Found in 60-80% of new diagnoses.

GADA: Glutamic acid decarboxylase. also present before the disease

IAA: Insulin autoantibodies. 100% of children diagnosed before age 5.
much lower after age 15.

Ia-2: Islet antigen 2

2

What are the classifications of diabetes mellitus?

Type 1
Type 2

LADA, type 1.5

Gestational Diabetes mellitus

Maturity Onset Diabetes of the Young: MODY
Caused by: Genetic defects of beta-cell functions

Gross/Exocrine Pancreatic defects: Pancreatitis, trauma, pancreatic cancer, cystic fibrosis.

Endocrinopathies: Acromegaly, Cushings, Hyperthyroidism, Pheochromocytoma.

Type 1 heritable non-autoimmune diabetes

3

Normal levels of glycated hemoglobin and its the abbreviation for glycated hemoglobin

Hb A1c

Greater than 6.5% is diabetic
4-6% is normal

4

Normal Albuminuria level

Low grade albuminuria

Macroalbuminuria:

< 20 ug/min
< 20 mg/day

20-200 ug/min

> 200 ug/min