Which statement is NOT true of PRIONS?
4
The correct answer is 4 because pathology is only observed in the CNS of the infected person or animal
Although prion infections are usually associated with consumption of contaminated meat, they also can be inherited and encoded in a person’s DNA
Prions convert normal proteins of the brain into pathogenic ones
This conversion is exponential and does take years to decades to complete
Which of the following bacterial populations would have the greatest size after 24 hours?
A) 10 cells with a doubling time of 8 hours
B) 100 cells with a doubling time of 12 hours
C) 1 cell with a doubling time of 2 hour
D) 1000 cells with a doubling time of 24 hours
C
Which event is an example of bacterial conjugation?
D

An increase in CHOLESTEROL has what impact on the plasma membrane?
A) increased membrane fluidity
B) increased solute transport across the membrane
C) decreased membrane fluidity
D) decreased solute transport across the membrane
A

Based on the data in Figure 2, what is a normal cellular progesterone level?

A) 0.19 ng/ml
B) 0.36 ng/ml
C) 38 ng/ml
D) 0.38 ng
B

A is incorrect because 0.19 ng/ml is outside that range
C is incorrect because 38 ng/ml is too large
This might be distracting, however, if you assume that the bar graph is telling you the progesterone concentration, since the bar for lane 1 is at approximately 38
Make sure when looking at a figure that gives multiple types of data that you know which data is coming from where
D is incorrect because 0.38 ng is not a concentration, it is merely a mass
H2O2 vs O2
Bond STRENGTH roughly correlates with bond….?
ORDER!
O2 is (+2)
H2O2 is (+1)
Therefore O-O bond in O2 is stronger
“Chelation”=?
“Chelation” describes a particular way that
ions and molecules
bind METAL IONS
Specifically: involves the formation or presence of two or more separate coordinate bonds between a multiple-bonded ligand and a single central atom

WHAT is the primary type of attraction that:
facilitates complimentary base pair matching?
What other kind of attraction can occur if this primary type is present?
H-bonding
is the primary type of attraction that facilitates complimentary base pair matching
Van der Waals attraction will also occur if molecules are hydrogen bound.
What is the synthetic purpose of the thermal decomposition of azobisisobutyronitrile (AIBN) in Step 2a?

A
A correct; tertiary radicals are most easily formed
In which solvent is P4 LEAST soluble?

A) H2O
B) CH3CH2OH
C) CH3COCH3
D) C6H6
A
Therefore, the most polar, and therefore LEAST likely to dissolve P4 among the choices listed is water, Answer A
What are the most likely sources of human dietary PHOSPHORUS?
A)protein and hydroxyappetite
B)protein and amino bisphosphonate
C)DNA and RNA
D)phosphoric acid and calcium
C
What is the EMPIRICAL formula for HYDROXYAPATITE?
Ca5(PO4)3OH
A) Pi electrons of the phenyl ring and the tertiary hydrogen
B) Pi electrons of the cyclohexenyl ring and the methyl group
C) Hydroxyl groups, epoxide oxygen lone pairs, and nitrogen lone pair
D) Only the lone pairs of the epoxide oxygen

C
In which concentration range would the paper-based lateral-flow test strip be most effective as a quantitative tool for predicting blood morphine levels based on test line intensity?
A) 1.0 – 100 ng/mL
B) 1.0 – 100 ng/mL
C) 0.1 – 1.0 ng/mL
D) 0.1 – 1.0 ng/mL

D
_VARY SUBSTANTIALLY_ and in a CONSISTENT DIRECTION
In the 0.1 to 1.0 ng/mL region:
A) 2.4 × 10–12 M
B)2.5 × 10–9 M
C) 2.4 × 10–6 M
D) 1.1 × 10–9 M

B
(7 x 10-1 ng/mL)
X (1 g/ 109 ng)
X (1 mol/3 x 102 g)
X (1 x 103 mL/L)
= 2.33 × 10–9 M
See picture

∆G’ = ∆G°’ + RTln [Products]/[Reactants]
=0.4 + (8.31)(310)(ln[0.01])
A PEPTIDE BOND differs from
most OTHER chemical bonds in that it features….?
What does this feature PREVENT?
RESONANCE between the C-O and C-N bonds

PREVENTING
FREE
ROTATION!!!
When a SPRINTER is running:
What is the SOURCE of the work done to accelerate Sprinter?
The GROUND is doing work on the SPRINTER
By definition, the force doing work on an object must be a force ON the object
A certain medical device converts the KE of high-velocity metal beads into HEAT energy
If 100% conversion efficiency were possible:
What MAXIMUM theoretical heat energy can be produced by a single chromium bead with:
(Density of Cr = 7,140 kg/m3)
1.4 x 102 J
Begin with the formula KE = 1/2mv2
KE = (0.5)(density)(volume)(velocity)2
However!!
Using dimensional analysis:
1x10-4 cm3 x (1m/100cm)3
= 1.0 x 10-10 m3
Now one can simply solve:
=½(7.1 x 103 kg/m3)(1.0 x 10-10 m3)(2.0 x 104m/s)2
This simplifies to:
= (3.5 x 103)(1 x 10-10)(4.0 x 108)
For an acid-base equilibrium at
CONSTANT TEMPERATURE:
which of the values listed is CONSTANT?
A) pH
B) Concentration of the conjugate base
C) Concentration of the weak acid
D) pKa
D
pKa is the ONLY constant among the answers
The acid-base equilibrium constant, Ka, is a constant for a GIVEN REACTION at a GIVEN TEMPERATURE
…Therefore the negative log of that constant would ALSO be a constant!
The pH of the solution is dependent on the concentration of acid and base in the equilibrium
The concentration of both the acid and the conjugate base can VARY depending on the reaction
Titrating aqueous AMMONIA with HCl
would produce a titration curve that looks like WHAT?
Because the titration starts out with
just the weak base present:
we need a plot that starts out basic, but not strongly basic

In the synthesis of tri-substituted oxazolidines the ACETYLENE acts as a:

A) Bronsted acid
B) Bronsted base
C) Lewis acid
D) Lewis base
C
The acetylenes contain an electron-deficient pi-systems making the double bond ELECTROPHILIC and susceptible to nucleophilic attack
“During normal growth, SOS pathway genes are repressed by LexA, which binds to the SOS box in the operator on either the coding strand or the template strand of the gene”
Q: The nucleotide sequence of the SOS box is most likely:
A) GAACGTTC
B) TATAAA
C) TAGTTGAT
D) GCGCCC
A
This tells you that the SOS box must be a PALINDROME!
In answer A, 5’- GAACGTTC- 3’
the compliment strand is 3’ –CTTGCAAG- 5’
…which is IDENTICAL when read 5’-3’
A) exactly 80m
B) one-half the force exerted by the biceps muscle group.
C) twice the force exerted by the biceps muscle group.
D) less than twice the force exerted by the biceps muscle group

D
When a person holds a mass steady with a bent elbow, the forearm is PREVENTED from moving either up or down
The MASS also acts DOWN on the forearm
at a lever arm of 40cm
The forearm itself has mass!
which can be assumed to act downward at approximately the center of the forearm
Therefore the bicep must counteract:
due to the co-directional torque resulting from mass m