Gonads and reproductive disorder lab diagnostics Flashcards Preview

Pathophysiology > Gonads and reproductive disorder lab diagnostics > Flashcards

Flashcards in Gonads and reproductive disorder lab diagnostics Deck (3):
1

1) The laboratory parameters of a 42-year-old man are: plasma prolactin and cortisol decreased, urinary 17-ketosteroid excretion is decreased, plasma prolactin level is not influenced by TRH. The administration of hCG increased the urinary excretion of 17-ketosteroids.
What is the possible diagnosis?

Panhypopituitarism

The hCG is a glycoprotein, with the same alpha chain, so it stimulated some androgen production, as LH and FSH would. 

MRI, CT for possible tumors, 

2

2) The laboratory parameters of a 19-year-old man are: plasma testosterone decreased, FSH and LH are elevated, urinary 17-ketosteroid excretion is decreased. The administration of hCG did not increase plasma testosteron level or the urinary excretion of 17-ketosteroids.
What is the possible diagnosis?

Primary hypogonadism. 

Check for:

cyrptorchidism 

fever, high body temp

trauma

mumps

 

3

3) The laboratory parameters of a 42-year-old man are: plasma testosterone increased significantly, FSH and LH are barely detectable, urinary excretion of androgens are increased. The right testis is enlarged.
What is the possible diagnosis?

Primary testosterone secreting testicular cancer.

or benign testosterone secreting testeroma.