Gonads and reproductive disorder lab diagnostics Flashcards Preview

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Flashcards in Gonads and reproductive disorder lab diagnostics Deck (3)
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1
Q

1) The laboratory parameters of a 42-year-old man are: plasma prolactin and cortisol decreased, urinary 17-ketosteroid excretion is decreased, plasma prolactin level is not influenced by TRH. The administration of hCG increased the urinary excretion of 17-ketosteroids.
What is the possible diagnosis?

A

Panhypopituitarism

The hCG is a glycoprotein, with the same alpha chain, so it stimulated some androgen production, as LH and FSH would.

MRI, CT for possible tumors,

2
Q

2) The laboratory parameters of a 19-year-old man are: plasma testosterone decreased, FSH and LH are elevated, urinary 17-ketosteroid excretion is decreased. The administration of hCG did not increase plasma testosteron level or the urinary excretion of 17-ketosteroids.
What is the possible diagnosis?

A

Primary hypogonadism.

Check for:

cyrptorchidism

fever, high body temp

trauma

mumps

3
Q

3) The laboratory parameters of a 42-year-old man are: plasma testosterone increased significantly, FSH and LH are barely detectable, urinary excretion of androgens are increased. The right testis is enlarged.
What is the possible diagnosis?

A

Primary testosterone secreting testicular cancer.

or benign testosterone secreting testeroma.