Flashcards in Part 2 Deck (60)
In systemic arteries, a small change in volume is associated with a?
Large change in pressure
In systemic veins, a large change in volume is associated with a?
Small change in pressure
What is 8x more distensible and 24x more compliant than systemic arteries?
Increased pressure tightens?
Decreased pressure loosens?
What causes osscilating pressure?
Change in blood volume
Local blood flow is regulated in proportion to the?
Metabolic Demand in most tissues
Short term control of blood flow involves vasodilation and vasoconstriction of?
Pre-capillary Resistent Vessels
Long term control of blood flow involves?
Changes in tissue vascularity
Changes in tissue vascularity includes?
1. Formation/Dissolution of Blood Vessels
2. Vascular Endothelial Growth Factor and Angiogenin
What acts as an integrator of multiple inputs?
Arterioles are richly innervated by SNS vasoconstrictor fibers and have?
Arterioles are effected by local factors which include?
Local vasodilators include?
PGE and PGI
With vasodilation decreased resistance will?
With vasoconstriction increased resistance will?
As tissue uses up oxygen, vascular smooth muscle cannot maintain constriction. This is known as?
Oxygen Demand Theory
The ability to keep blood flow constant in the face of a changing arterial BP is called?
Most tissues show some degree of?
In the kidney, both renal flow and glomerular filtration rate (GFR) are?
Long term control of flow involves changes in?
What is the production of new micro vessels?
Shear stress caused by enhanced blood flow velocity associated with partial occlusion is called?
Angiogenic factors are small peptides that stimulate?
Growth of new vessels
Angiogenic factors were first isolated from?
Stress activated endothelium up-regulates the expression of?
Monocyte Chemoattractant Protein-1 (MCP-1)
MCP-1 attract proteins that?
Other adhesion molecules and growth factors participate with MCP-1 during?
Hypoxia causes the release of?