Flashcards in Part 5 Deck (56)
Arterial pressure controls?
Renal-body fluid system
In the renal-body fluid system, increased ECF will cause?
Arterial pressure to rise
Renal-body fluid system, in response to kidneys will?
Excrete excess ECF
The degree of shift of the renal output curve for water and salt is known as?
Determinants of long term arterial pressure
Increased total peripheral resistance will not create a long term elevation of of BP if?
Fluid intake and renal function don't change
In the kidney, afferent arterioles supply the glomerular capillaries where?
Filtration takes place
Efferent arterioles drain the glomerular capillaries which give rise to peritubular capillaries where?
Reabsorption takes place
Specialized peritubular capillaries associated with juxtamedullary nephron's is called?
When the ECF levels rise, the arterial pressure?
The kidneys excrete more fluid, thus bringing the pressure?
Back to normal
Acute renal output curves have the effect of?
Arterial pressure alone
Chronic renal output curves have the effect of arterial pressure plus?
What hormones decrease renal blood flow?
What hormones increase renal blood flow?
Prostaglandins E and I
What monitors NaCl in the macula densa of the distal tubule?
Decreased NaCl in the macula densa will cause renin to be released from?
Increased renin will increase angiotensin II levels which will increase?
Efferent Arteriole resistance
Decrease NaCl in the macula densa also causes?
Dilation of afferent arteriole
The renin-angiotension-aldosterone system provides the source of?
What synthesizes, stores and releases renin?
Smooth muscle cells in afferent arterioles
Renin is stimulated by?
Decreased perfusion pressure
Decreased NaCl to macula densa (distal tubule)
What hormones stimulate renin?
Renin is an enzyme that catalyzes the formation of?
Angiotensin I (10 AA) from Angiotensinogen (liver)
What occurs primarily in the lung via angiotensin converting enzyme associated with pulmonary endothelium?
Angiotensin 1 --> Angiotensin II
What are the functions of angiotensin II?
Stimulates adrenal cortex to secrete aldosterone
Stimulates release of ADH/Vasopressin
The net effect of the functions of angiotensin II is?
decrease Na+ and H2O which increase BP
Angiotensin II will also stimulate thirst/drinking behavior at the level of the?
When you tie off one renal artery you can develop?
Systemic hypertension elevates?
Renin and Angiotensin II