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1

Why shouldn’t Cordarone be given with sofosbuvir-containing regimens?

Serious symptomatic bradycardia

2

How should patients take the Viekira Pak tablets?

2 pink tablets + 1 beige tablet in morning, 1 beige tablet in the evening
(Beige tablet is dasabuvir)

3

What medications are Viekira Pak contraindicated in combination with?

Ethinyl estradiol, lovastatin, simvastatin

4

What warnings are associated with interferons?

May cause or aggravate:
1. Autoimmune disorders
2. Psychiatric symptoms
3. Ischemic disease
3. Infections

5

What lab abnormalities are indicative of chronic liver disease?

Hypoalbuminemia and increased INR

6

ANC calculation

WBC x % neutrophils (segs + bands) x 10

7

Why should acetaminophen be used instead of NSAIDs in patients with cirrhosis?

NSAIDs can precipitate GI bleeding, blunt the diuretic response, and exacerbate renal dysfunction. APAP is safer if used sparingly at reduced doses.

8

Which natural product is used as a liver-protective agent?

Milk Thistle

9

What is a non-pharmacological recommendation for managing hepatic encephalopathy?

Restricting animal protein intake

10

What pharmacologic category is Transderm Scop?

Anticholinergic

11

Transderm Scop counseling points

1. May cause dry mouth, dizziness and confusion
2. Do not use alcohol
3. Can make patient tired; don't operate heavy machinery

12

Why can scopolamine worsen glaucoma?

anticholinergics can increase intraocular pressure and worsen glaucoma

13

Which BZDs are considered most safe in patients over the age of 65 based on Beers Criteria?

Lorazepam, oxazepam, temazepam

14

Which natural products can be used for anxiety?

Valerian, kava, St. John's Wort, passionflower

15

USP chapter for non-sterile compounding

USP 795

16

What is Onzetra Xsail?

Intranasal sumatriptan

17

What treatment could be used for a 13-year old suffering from frequent migraines?

Maxalt (At least 6), Zolmiptriptin nasal and almotriptan and Treximet (at least 12)

18

How to take CellCept?

Twice daily on empty stomach, 12 hours apart

19

Common live vaccines that should be avoided in transplant patients

intranasal FluMist, MMR, Varivax (chicken pox), Zostavax (shingles)

20

Brand name(s) of everolimus

Afinitor, Zortress

21

Which cancers are transplant patients at higher risk for?

Melanoma, lymphoma

22

How often should the following be performed at minimum:
1. glove fingertip testing
2. air sampling
3. temperature check
4. air pressure check

1. annually
2. every 6 months
3. daily
4. daily

23

How often should media fill testing for technicians be performed?

Annually for medium- and low-risk compounding
Semiannually for high-risk compounding

24

What is considered high-risk compounding?

Making a CSP from non-sterile ingredients

25

Which reagent is used for the bacterial endotoxin test (BET)?

Limulus Amebocyte Lysate (LAL) is used for the BET to test for pyrogens

26

Brand name of calcium polycarbophil

Fibercon

27

Alvimopan

Entereg, opioid receptor antagonist for prevention of post-op ileus
(REMS drug, max 15 doses)

28

What are the peripherally acting mu-opioid receptor antagonists for constipation?

Methylnaltrexone (Relistor)
Naloxegol (Movantik)
Naldemedine (Symproic)

29

Lubiprostone

Amitiza for opioid induced constiption

30

Linaclotide (brand, MOA, tx)

Linzess, agonist of guanylate cyclase C, treats chronic idiopathic constipation (or IBS-C)