For every hormone, what core categories should you be able to identify?
Gland, hormone released, target cells, physiologic function, hyperfunction signs, hypofunction signs, regulating axis, and whether disease is primary, secondary, or tertiary.
Why does the instructor emphasize thinking in systems rather than isolated facts?
Because endocrine function depends on organized axes, feedback loops, and predictable patterns of dysfunction.
What universal framework can be used to study any endocrine gland?
A chart including gland, hormones, targets, function, hyper state, hypo state, regulating axis, feedback type, and disorder level.
What does “hyperfunction” of a hormone mean?
Excess hormone causing exaggerated normal effects.
What does “hypofunction” of a hormone mean?
Deficient hormone causing loss of normal effects.
Why are diseases useful for learning endocrine physiology?
Because disease symptoms reflect what the hormone normally does.
What hormones are produced by the thyroid gland?
T3 (triiodothyronine) and T4 (thyroxine).
What cells are targeted by thyroid hormones?
Nearly all cells in the body.
What is the primary physiologic function of thyroid hormones?
Regulation of metabolism and heat production.
What are classic signs of hyperthyroidism?
Increased temperature, sweating, tachycardia, nervousness, and weight loss.
What are classic signs of hypothyroidism?
Cold intolerance, fatigue, decreased temperature, and weight gain.
What is the hormone axis that controls thyroid function?
Hypothalamus (TRH) → Pituitary (TSH) → Thyroid (T3/T4).
What type of feedback regulates the thyroid axis?
Negative feedback.
How does negative feedback work in the thyroid axis?
High T3/T4 suppress TRH and TSH release upstream.
What defines a primary endocrine disorder?
The problem originates in the target gland.
What defines a secondary endocrine disorder?
The problem originates in the pituitary gland.
What defines a tertiary endocrine disorder?
The problem originates in the hypothalamus.
Why can primary, secondary, and tertiary disorders present with similar symptoms?
Because hormone effects on target tissues may be similar despite different causes.
What is the key difference between primary, secondary, and tertiary disorders?
The location of the failure in the endocrine axis.
What does the general endocrine control hierarchy look like?
Hypothalamus → Pituitary → Target gland → Target tissues.
What does HPT stand for?
Hypothalamic–Pituitary–Thyroid axis.
What does HPA stand for?
Hypothalamic–Pituitary–Adrenal axis.
What does HPG stand for?
Hypothalamic–Pituitary–Gonadal axis.
Which type of feedback is most common in the endocrine system?
Negative feedback.