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SADL Oncology > supportive care > Flashcards

Flashcards in supportive care Deck (12):
1

for F+N which patients would you consider adding vancomycin?

-AML patients receiving high dose cytarabine, due to risk of S.viridans infection associated with septic shock and ARDS
-presented with hypotension/shock
-mucositis
-prior history of alpha hemolytic strep infection
-colonization with resistant bugs
-vegetations on echo

2

for F+N when would you consider adding flagyl?

-typhlitis
-significant mucosal breakdown
-perianal skin breakdown
-c-diff infection
-peritoneal signs or other abdominal pathology

3

what infections are BMT patients at risk for within the first 30 days post BMT?

gram negatives
staph
aspergillus
candida
HSV-1

4

what infections are BMT patients at risk for within 30-120 days post BMT?

candida
aspergillus
PJP
CMV, adeno, EBV, HHV-6

5

what are three findings on imaging that suggest Invasive fungal infection of lower resp tract?

dense circumscribed lesion with or without halo sign
air crescent sign
cavitation

6

what is the best antifungal to use to treat aspergillus

voriconzole

7

amphotericin does not cover which species of candida the best and is not recommended?

candida albicans
fluconazole is the treatment of choice

8

what is the treatment of choice for mucormycosis

Ampho B

9

for neutropenic patients what is the initial therapy for candidemia?

echinocandin is the therapy of choice
Ampho B is an alternative

10

What are the principles of chemotherapy?

- multi-drug therapy
- neo-adjuvant vs adjuvant therapy
- dose intensity

11

Identify 2 subtle CT signs suggestive of invasive aspergillosis.

- halo sign
- air-crescent sign

12

Identify 3 ethical principles of TCSP2

Respect for persons
Concern for welfare
Justice