02a: Cervical Flashcards Preview

Oncology > 02a: Cervical > Flashcards

Flashcards in 02a: Cervical Deck (20)
Loading flashcards...
1
Q

Squamous cell carcinoma of cervix peAk incidence at what age?

A

40-45

2
Q

Cervical LSIL (low grade squamous intraepithelial lesion): what are the chances the lesion will regress, persist, and progress to HSIL?

A

Regress: 60%
Persist: 30%
Progress: 10%

3
Q

Cervical HSIL (high grade squamous intraepithelial lesion): what are the chances the lesion will regress, persist, and progress to carcinoma?

A

Regress: 30%
Persist: 60%
Progress: 10%

4
Q

T/F: in both malignant and benign HPV lesions, the virus integrates into host DNA.

A

False - integration important in malignancy

BUT in benign warts/paraneoplastic lesions, virus is free

5
Q

Which drugs/substances increase risk of cervical cancer?

A

Oral contraceptives and nicotine

6
Q

Pap smear: metabolically inactive cells are stained (X). Metaplastic squamous cells stained (Y)

A
X = pink
Y = blue green
7
Q

Women with normal pap and negative HPV DNA should be screened again every:

A

3 years

8
Q

Women with normal pap and positive high risk HPV DNA should be screened again every:

A

Rescreen again at 6-12 mo

9
Q

Cervical cancer staging: stage 0

A

CIN (cervical intraepithelial neoplasia) 3 (full thickness of epithelium)

10
Q

Cervical cancer staging: stage 1

A

Carcinoma (breached BM) confined to cervix

11
Q

Cervical cancer staging: stage 2

A

Tumor extends beyond cervix (not onto pelvic wall) and into vag but not lower 1/3

12
Q

Cervical cancer staging: stage 3

A

Involves pelvic wall or lower 1/3 of vag; regional node metastasis

13
Q

Cervical cancer staging: stage 4

A

Beyond true pelvis, mucosa of bladder/rectum and/or metastasis

14
Q

Bethesda System establish to report (X)

A

X = Pap smears

15
Q

Cervical cancer: 5y survival for stage III is (X). And stage IV is (Y)

A

X = Y = under 50%

16
Q

Cytopathology is study of (normal/abnormal) (X) cells in tissue fluid.

A

Both normal and abnormal

X = exfoliated (shed)

17
Q

Give examples of natural spontaneous exfoliation of tissue used in cytopathology

A
  1. Skin, vag/cervix
  2. Gland secretion (ex: nipple)
  3. Sputum
  4. Urine
18
Q

T/F: exudates and transudates can be evaluated by cytopathology

A

True (pleural, pericardial, peritoneal, joint, CSF)

19
Q

T/f: scraping cells from cervix, oral cavity, skin is considered natural spontaneous exfoliation for cytopathology

A

False - artificially enhanced exfoliation

20
Q

List disadvantages of cytopathology

A
  1. Interpret of cell morphology based only on individual cell observation
  2. Can’t always diagnose - may need histo confirmation
  3. Doesn’t always determine size/type of lesion