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Flashcards in C diff Deck (7)
1

Characteristics of BI/NAP1/027

high level fluoroquinolone resistance
efficient sporulation
high toxin production
death 3 x normal
more likely to fail treatment with metro

2

WCC in C diff

up

3

ELISA detects
DNA based tests ID

toxins
toxin genes

PCR for toxin is most sens and spec

4

hypervirulent strain mech

deleted tcdC gene which normally represses toxins A and B production

5

wash hands with

soap and water- spores

6

second relapse

fidaxomicin (does not work in NAP1 strains)

or

tapered and pulsed vanc

7

treatment

mild to mod- metro
severe- oral vanc

if very severe add IV metro to oral vanc