chapter 4 part 3

Question 1

2 questions that geneticists ask when organisms have same mutant phenotype

Answer 1

1. do these organisms have mutations in the same or different genes?
2. how many genes are responsible for the mutations?

Question 2

genetic complementation analysis

Answer 2

performed by mating 2 pure-breeding mutants for similar mutant phenotypes and observing phenotypes in F1 generation

Question 3

if phenotypically wild type offspring obtained from genetic complementation analysis:

Answer 3

• mutations in parents must be in 2 different genes
• complementation has occurred

Question 4

if phenotypically mutant offspring obtained from genetic complementation analysis:

Answer 4

• mutations in parents must be in same gene
• complementation has not occurred

Question 5

genetic heterogeneity

Answer 5

described conditions when mutations in different genes can produce the same or very similar mutant phenotypes