Flashcards in Chapter One - Epithelium Deck (123)
What are the four basic types of tissue?
Epithelial, muscle, nervous, and connective
What are the three general functions of epithelium?
Absorption, secretion, and providing a barrier
Which general function of epithelium is a function of ALL epithelium?
Providing a barrier
What produces the basal lamina of the basement membrane?
What are the three specialized functions of epithelium?
Transfer molecules across epithelium, prevent transfer of materials (aka selective permeability), sensory function
What produces the reticular lamina in the basement membrane?
Fibroblasts in connective tissue
What are the two parts of the basement membrane of epithelium?
Basal lamina and reticular lamina
What makes up a partial basement membrane of epithelium?
Basal lamina ONLY
What are the functions of the basement membrane of epithelium?
Providing a surface for epithelial cell attachment, molecular filter (very limited), limits stretch, and directs migration of cells
Are epithelial cells vascular or avascular?
By what process do epithelial cells obtain nutrition?
What are the functions of connective tissue?
Provides nutrition (and oxygen), source of defensive cells
Which type of cell junction involves the sharing of intrinsic membrane proteins between adjacent cells?
What is the other name for zonula occludens?
What are the functions of zonula occludens (tight junctions)?
Provides strong attachment, prevents the passage of materials between cells
Zonula adherens consist of what?
Cadherins (linkage proteins) and marginal bands (microfilaments)
What part of the zonula adherens are located between cells?
What is the other name for zonula adherens?
What part of the zonula adherens attach the cytoskeleton to the cell membrane?
What are the functions of the zonula adherens?
Strong attachment and provide cell structural stability
What is another name for macula adherens?
What is the function of macula adherens?
Provides strong attachment
What are the three parts of the macula adherens?
Transmembrane proteins, protein plaque, and tonofilaments
Which type of cell junction is arranged in a cylinder with six connexins (proteins)?
What are the two functions of gap junctions?
Strong attachment, transport materials between cells
What makes up the junctional complex (in order)?
Zonula occludens, zonula adherens, macula adherens
What junctions hold the epithelium to the basement membrane and the connective tissue below?
Hemidesmosomes and focal point contacts
What is the function of hemidesmosomes?
Helps connect epithelial cells to the basal lamina (essentially half a desmosome)
What is bullous pemphigoid?
An autoimmune skin disease causing large blistering lesions that burst but do heal