Coversyl Plus

Question 1

Drug Class

Answer 1

ACE Inhibitors

Question 2

Active

Answer 2

Perindopril and indapamide

Question 3

Indications

Answer 3

• Hypertension
• Heart Failure
• Diabetic nephropathy and prevention of progressive renal failure in patients with persistent proteinuria
• Post MI
• Reduction of risk of cardiovascular events in specific patients
• Asymptomatic left ventricular dysfunction

Question 4

Dose Range

Answer 4

2.5 – 10 mg daily

Question 5

SE’s

Answer 5

• hypotension
• hyperkalaemia
• persistent dry cough (inhibit the breakdown of bradykinin)
• dizziness
• fatigue
• renal impairment
• angioedema
• anaphylactoid reactions
• taste disturbance (metallic)

Question 6

Counselling

Answer 6

Labels: 11, 12+, 16

• You may feel dizzy when you start taking this medicine. Get up gradually from sitting or lying to minimise this effect; sit or lie down if you become dizzy or light-headed.
• Do not take potassium supplements while you are taking this medicine unless your doctor tells you to.
• If swelling of face, lips or tongue is experienced, seek medical advice

Question 7

Monitoring

Answer 7

• BP
• SE’s: Dry Cough
• Renal function
• Electrolytes (in particular K levels)