Esomeprazole

Question 1

Drug Class

Answer 1

Proton Pump Inhibitor (PPI)

Question 2

Active

Answer 2

Esomeprazole

Question 3

Indications

Answer 3

• Peptic ulcer disease (PUD)
• GORD
• Dyspepsia
• H. pylori eradication
• Prevention and/or treatment of upper GI adverse effects of NSAIDs
• Zollinger-Ellison syndrome
• Scleroderma oesophagus
• In selected patients for stress ulcer prophylaxis, acute upper GI bleeding, prevention of acid aspiration

Question 4

Dose Range

Answer 4

20-80mg daily

Question 5

SE’s

Answer 5

Well Tolerated

• headache
• n/v
• diarrhoea
• abdo pain
• dizzy,fatigue
• flatulence, constipation
• reduced vit B12 absorption

Question 6

Counselling

Answer 6

• With tablet, swallow WHOLE (do not crush or chew) or you can disperse it in water, then drink within 30 minutes.
• Tell your doctor if you develop symptoms such as black stools or vomit that looks like coffee grounds.

Self care:
- Try to identify and avoid things that make your symptoms worse. Simple changes to diet and lifestyle that can
often prevent or reduce the symptoms of indigestion and heartburn include:
• Eat less fatty and spicy food, chocolate, peppermints and other known problem foods
• Eat smaller meals
• Eat slowly and chew food well
• Drink less alcohol
• Have less caffeine (e.g., coffee, tea, cola, energy drinks)
• Don’t eat for 2–3 hours before going to bed
• Do not slump in a chair, bend over or lie down soon after meals
• Go for a short walk after your main meal
• Wear loose clothing around your waist
• Elevate the head of the bed
• Reach and keep to a healthy weight
• Don’t smoke
• Learn and practice relaxation techniques to manage stress.

Question 7

Monitoring

Answer 7

• Effectiveness of medication (reduce if no longer needed)

- SE’s: black stool or coffee coloured vomit