CSF

Question 1

What is Froin’s Syndrome? What triad characterizes is?

Answer 1

Characterized by the triad of: 1. Xanthrochromia 2. CSF coagulation 3. CSF protein increased (up to 1000)

Generally occurs whenever there is obstruction to flow causing stasis or if the CSF becomes loculated

Question 2

What RBC to WBC ratio defines a traumatic tap?

Answer 2

at least 700 RBCs per 1 WBC

Question 3

What cellular mechanism is fundamental to CSF production?

Answer 3

Na/K ATP pump

Question 4

What nucleus and molecule control CSF production?

Answer 4

Raphe Nucleus sends serotonin to periependymal vessels

Question 5

What two factors can increase production of CSF?

Answer 5

Volatile Anesthetics and CO2

Question 6

What two factors decrease production of CSF?

Answer 6

Carbonic anhydrase inhibitors (acetazolamide) and Norepinephrine

Question 7

How much CSF is produced per hour? Per day? What is the total volume of CSF?

Answer 7

20 mL/h

450 mL/day

150 mL total

Question 8

What comprises the choroid plexus?

Answer 8

single layer of cuboidal epithelial cells surrounding blood vessels

Question 9

Where are the primary locations of choroid plexus?

Answer 9

1. Roof of the 4th ventricle
2. Inferior Medullary Vellum
3. Lateral Recess to the foramen of Luschka
4. Posterior roof of the 3rd Ventricle
5. Floor of the body of the Lateral Ventricle
6. Roof of the temporal horn of the lateral ventricle