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Flashcards in injectables Deck (10):
1

Propofol
(onset? route? side-effects? shelf life?)

-fast acting and lasts 10-15 minutes (safe for CRI)
-no problem if given perivascular
-short cardiovascular depression
-apnea, resp. depression, decrease CO -> increased HR
-CNS friendly (dec. ICP, protective for brain ischemia) *but seizure like activity after eliminated*
-contamination after 6hrs (bc of Egg lecithin), but with 2% Benzyl Alcohol, shelf life increased to 28 days (2 yr unopened)

2

Ketamine

-Dissociative, Analgesic, increases sympathetic tone
-poor muscle relaxant (use Benzodiazapine for induction), maintained reflexes
-violent recovery
-increases ICP, CBF, IOP
-decreases seizures threshold
-apnea, apneustic breathing
-increases myocardium work load

3

Telazol

-Dissociative like ketamine but comprised of 1:1 Tiletamine and Zolazepam
-smaller volume (powder used with sterile water)
- side-effects mimic ketamine
-rough recovery without pre-meds
-can be constituted with Ketamine and Alpha 2

4

Etomidate

-minimal cardiovascular changes, good for cardiac patients
-adrenal suppression (so don't use on septic patients!)
-poor muscle relaxation
-combined with opioid or benzo for induction
-expensive

5

Opioids

-fentanyl (short acting) or hydromorphone (long acting) bolus
-decreases HR and ventilation
-reversible
-analgesic
-no myocardial depression
- inc. ICP if hypoventilating

6

Alfaxalone

-fast acting
-no problem perivascular
-short cardiovascular depression
-apnea, respiratory depression
-CNS friendly
-can be given IM

7

Generally anesthetics are ____soluble and ________.

liposoluble and highly protein bound.

8

What causes an animal to wake up from anesthesia?

REDISTRIBUTION of the drug

9

Once tissues are saturated with a drug what will decrease plasma concentration of the drug?

Elimination

10

Injectable anesthetics that can be given IM?

Ketamine and Alfaxalone