What is a spontaneous abortion?
Pregnancy that ends before 20 weeks gestation
MC etiology of spontaneous abortion
Chromosomal abnormalities
Symptoms of threatened abortion
- Cervical Os closed
Symptoms of inevitable abortion
- Cervical OS dilated
Symptoms of incomplete abortion
- Cervical OS dilated
For a missed abortion, the cervical OS is _____ and POC are _____
Closed
Intact
For a medical abortion what two medications are used and is safe up to 10 weeks?
Mifepristone followed by Misoprostol 24-48 hours later
For a medical abortion, what medications are used and is safe up to 7 weeks?
Methotrexate followed by Misoprostol 3-7 days later
What methods are used for surgical abortion?
-Dilation and curettage or dilation and evacuation
How to tell, on diagnostics, if a mother is having multiple gestations
-Elevated levels of beta-hCG and maternal serum alpha-fetoprotein
Fundal Height Measurement
Gravida: ______
Para: ______
Abortus: ______
What is Naegele’s Rule?
1st day of LMP + 7 days - 3 months
The first trimester consists of weeks ______
1-12 of pregnancy
Tests done in 1st trimester
-Chromosomal screening test: Free beta-HCG, PAPP-A, Biochemical screening, US, chorionic villous sampling, nuchal translucency US
PAPP-A is low with
Down’s Syndrome
In a nuchal translucency US, is increased thickness, what test is done?
Chorionic villous sampling or amniocentesis
Transvaginal US can detect fetal heart activity as early as
5-6 weeks after LMP
Second Trimester consists of weeks
13-27
What tests are done in second trimester?
Two MC types of neural tube defects
-Spina Bifida and Anencephaly
What is anencephaly?
-Failure of closure of portion of neural tube that becomes cerebrum
What is spina bifida?
-Incomplete closure of embryonic neural tubule leads to non-fusion of some of the vertebrae and some overlying the spinal cords.
What is the MC type of spina bifida
With myelominingocele. Often leads to disability