(true/false) BDNF is a neurotransmitter
false
What pathway is responsible for fast and localizing pain?
neospinothalamic pathway
What pathway is responsible for slow/gradual pain and dull pain?
paleospinothalamic pathway
What pathways make up the paleospinothalamic pathway?
spinoreticular
spinomesencephalic
spinolimbic
What system is the paleospinothalamic and neospinothalamic pathway a part of?
anterolateral system
What is the reticular formation responsible for?
attention
What structures of the brain are responsible for the afferent part of pain?
What structures of the brain are responsible for attention and cognititon?
What lobe is the amygdala a part of?
temporal lobe
What is the function of the amygdala?
emotion
What causes neuropathic pain?
Damage to a nerve
(DM, shingles, amputations)
definition: pain that exists AFTER the stimuli causing the pain is gone
chronic pain
What descending systems help with pain modulation?
PAG
locus ceruleus
raphe system
The raphe system inhibits ____ input going to the cortex.
C fiber
definition: pain from the nerve itself
neuropathic pain
(true/false) CRPS is normally caused by a noxious event and is hard to control.
false (not caused by a noxious event)
What are the s/s of type I CRPS?
definition: touching an area and causing pain strictly through mechanoreceptors
allodynia
Fibromyalgia affects (males/females) more.
females
What is the s/s of fibromyalgia?
TTP pain
What are the mechanisms that cause chronic pain?
definition: As damage to a nerve tries to regenerate, the axons converge due to not enough myelin separating them (therefore, doubling the effect)
ephaptic transmission
definition: a mild stimulus causes an increase in neurotransmitters within the spinal cord due to sensitization of the pathway
wind up
In allodynia, the _____ will activate the painful pathway.
mechanoreceptor